Patients with positive coronavirus infection are included in the study based on PCR and CT scan findings. The onset of symptoms is assessed based on the patient's history, initial imaging findings, and PCR. Patient symptoms including sore throat, dry cough, chills, diarrhea, fever, and other symptoms are recorded. Fifty patients are allocated to intervention and control groups. Twenty-five patients receive 20 mg of isotretinoin twice daily for 7 days along with the standard of care treatment. Other patients receive the standard of care according to the national guidelines.
Preliminary data include CT scan findings, clinical signs (fever, fatigue, dry cough, anorexia, shortness of breath, purulent discharge), pulse oximetry findings, and arterial blood gas tests are recorded and analyzed.