Block randomization: For this study, a specific population of unfertilized diminished ovarian reserve patients was chosen, admission and exclusion criteria from the study were chosen very detailed and accurate. all the population was all the same in the range of age and weight, non-fertility period, normal sperm analysis of their spouses, therefore block randomized of 180 patients were divided into main group (A), control group (B). hence 18 blocks of 10 were created using Computer logarithm from the study randomized app (https://app.studyrandomizer.com). All the blocks were the same and both groups contained the same amount of samples (1:1), the state of each block was different from the next block.
randomizing the samples was conducted as follows: First, based on a computer logarithm 180 sample (patient) was randomized. and for each sample, block identifier, block size, sequence within the block was designed. For example, the code 2,6,1 shows that the second patient in block no. 1 of 10 is located in the second seat. for each patient, a specific code (study ID) was defined based on standard coding, and therefore the master randomized list was created for the patients.