Effect of one to four-week omega-3 consumption on muscle damage indices after an eccentric exercise session

The purpose of this study is evaluate the effect of1to 4-week omega-3 consumption on muscle damage indices after eccentric resistance exercise

A clinical trial with control group, with parallel group, triple-blinded and randomized on 60 subjects; using random number table for simple randomization

The study will be conducted at the Iran Football Medical Assessment and Rehabilitation Center (IFMARK).After receiving informed consent,participants will receive a nutritional questionnaire that records their diet for 12days, 3days a week, and then will be evaluated using NUTRITION4 software. After7days of the 1RM session ,supplementation will be begun. the subjects will be randomly divided into 6 groups of12 people The last supplement will be received8 hours before the eccentric resistance exercise. Before performing the exercise program, a blood sample test will be received from subjects to measure the levels of CK enzyme activity and LDH activity. The muscle pain perception will also be evaluated

Entery conditions:males with normal weight( 18/5<BMI<24/9).Exit condition: having a history of sports activities;taking dietary supplements,medication and painkillers;following a diet other than the general pattern of Iranian diet and following a special diet

Intervention group1: 1week omega-3, 1200mg(EPA=720 and DHA=480),twice a day, for 1 week/ Intervention group2: 2 weeks omega-3, 1200mg(EPA=720 and DHA=480), twice a day, for 2 weeks/study group3: 3weeks omega-3, 1200 mg(EPA=720 and DHA=480), twice a day, for 3 weeks/Intervention group4: 4weeks omega-3,1200mg (EPA=720 and DHA=480), twice a day,for4 weeks/Control group1: sunflower oil capsules(placebo),1200mg, twice a day, for 4 weeks/ Control group2: without supplementation.

Serum creatine kinase enzyme; serum lactate dehydrogenase enzyme; muscle pain perception

The 60 subjects will be divided into six groups of ten using simple randomization method and by random number table. First, a list of all participants will be provided and the names from the list will be deleted. Then, using the random number table, the researcher will start from a random point and moves through the the row from left side, and assigns each selected number to each study group, randomly. This will continue until the number of people in each group is completed. Therefore, the researcher will not have the opportunity to change the status of the assignment of individuals or predict it.

The data analyst, outcome assessor, researcher and participants in the study do not know who is in the intervention groups and who is in the placebo group.

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