The aim of this study was to evaluate the therapeutic effects of coffee and/or honey in the treatment of patients with Persistent Post-infectious Cough. A total of 74 adult participants who had experienced PPC longer than 3 weeks, were assigned into the following three groups. For all the participants a jam-like paste was prepared. Each 600 grams of the product consisted of "70 grams original instant coffee" in the first group,"500 grams of honey" in the second group, and "70 grams of instant coffee plus 500 grams of honey" in the third group. These participants were told to dissolve 25 grams of the prescribed product in about 200 cc of warm water (under 60 C), and drink this solution every 8 hours for one week. Frequency of cough was evaluated for before and after the treatment and also a month after the intervention and compared between groups.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT201009134737N1
Registration date:2011-01-26, 1389/11/06
Registration timing:retrospective
Last update:
Update count:0
Registration date
2011-01-26, 1389/11/06
Registrant information
Name
Mohammad Ali Raeessi
Name of organization / entity
Baqiyatallah University of Medical Sciences and Health Services
Country
Iran (Islamic Republic of)
Phone
+98 21 8803 0514
Email address
raeessi@bmsu.ac.ir
Recruitment status
Recruitment complete
Funding source
Baqiyatallah University of Medical Sciences
Expected recruitment start date
2003-01-01, 1381/10/11
Expected recruitment end date
2009-12-29, 1388/10/08
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Honey with Coffee: A new finding in treatment of Persistent Postinfectious Cough
Public title
Honey with Coffee: A new finding in treatment of Persistent Postinfectious Cough
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: PPC for more than three weeks of duration, normal routine laboratory tests, no systemic disease, normal chest X-Ray, age between 21 and 65 years
Exclusion criteria: presence of any systemic disease, other causes of chronic cough
Age
From 20 years old to 65 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
74
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethic Committee in Medical Sciences Research, Deputy of Research and Technology, Baqiyatallah Univer
Street address
Sheikhbahaee St., Mollasadra Ave.
City
Tehran
Postal code
Postcode: 14359
Approval date
2010-09-22, 1389/06/31
Ethics committee reference number
2684
Health conditions studied
1
Description of health condition studied
persistent post infectious cough
ICD-10 code
J31.2
ICD-10 code description
Chronic pharyngitis
Primary outcomes
1
Description
Persistent postinfectious cough (PPC)
Timepoint
before and after the treatment
Method of measurement
frequency of cough: low (+), moderate (++), and high (+++)
Secondary outcomes
empty
Intervention groups
1
Description
Coffee: 25 grams of the jam-like paste (Each 600 grams of the product consisted 70 grams of original instant coffee) is dissolved in about 200 cc of warm water (under 60 degree C) and drunk every 8 hours for one week.
Category
Other
2
Description
Honey: 25 grams of the jam-like paste (Each 600 grams of the product consisted 500 grams of honey) is dissolved in about 200 cc of warm water (under 60 degree C) and drunk every 8 hours for one week.
Category
Other
3
Description
Coffee and honey: 25 grams of the jam-like paste (Each 600 grams of the product consisted 500 grams of honey as well as 70 grams of original instant coffee) is dissolved in about 200 cc of warm water (under 60 degree C) and drunk every 8 hours for one week.
Category
N/A
Recruitment centers
1
Recruitment center
Name of recruitment center
Baqiyatallah Hospital - Baqiyatallah University of Medical Sciences and Health Services
Full name of responsible person
Dr. Chaboki
Street address
Mollasadra Ave.
City
Tehran
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Mohammad Ali Raeessi + Baqiyatallah University of Medical Sciences and Health Services