Comparing effect of tamsulosin drug and Lithorex B on renal colic and the expulsion of renal stone and urinary stones after extracorporeal shock wave lithotripsy (ESWL)

Background: Our aim was to compare oral tamsulosin and Lithorex B for treatment of renal colic and stone passage after extracorporeal shockwave lithotripsy (ESWL) Methods: In this randomized clinical trial from March 2014-2016 sixty four (64) patients with renal and upper ureteral stones with size less than 20 millimeter that referred to Shahid Beheshti Hospital of Yasuj after taking informed consent form and approval of ethics committee are divided into two groups by simple sampling method. In all patients completed history and physical exam was done and basal serum samples was checked. Patients who have coagulopathy; active infection; azotemia; uncontrolled hypertension; hypersensitivity to narcotic or analgesic drugs and pregnant women were excluded. Then in both groups extracorporeal shockwave lithotripsy was done. Then patients were observed for two hours and if patient have no complication, they will be allocated in two groups. In both groups it has been offered that patients should drink 10-12 glasses of water every day. In first group one tablet of Lithorex B was prescribed by one glass of water every 8 hour. In the second group a capsule of tamsulosin was prescribed with one glass of water every night. Two weeks later patients were visited again and KUB or ultrasonography was done and efficacy of treatment according to change in the size of stone and the existence of residual stones were measured and recorded. The pain intensity of patients’ before and after ESWL and during taking drugs measured and recorded by means of visual analog scale.

Research vice chancellor, Yasuj University of Medical Sciences,