RA simple randomization method was used to assign individuals to two groups, which was done by coin tossing method. This method is usually used to create a random sequence in two-group experiments in such a way that one of the study groups considers the lion and the other group the line, and based on the sample size, coins were tossed and Individuals are assigned to two random groups. In order to make it clear that before allocating people to two groups, it is not clear to which group individuals will be assigned, or in other words, hiding the random allocation (Allocation concealment) by the method of opaque envelopes sealed with sequentially randomized sequence (Sequentially numbered, sealed opaque envelopes) was used. This method is one of the common methods in concealing random allocation, which is abbreviated to SNOSE method. In this method, after a random sequence, a number of envelopes are prepared and each of the random sequences created is recorded on a card and the cards are placed in the envelopes respectively. In order to maintain a random sequence, the envelopes are numbered in the same way on the outer surface. Finally, the letter envelopes are glued and placed in a box, respectively. At the beginning of the registration of participants, based on the order of entry of eligible participants into the study, one of the envelopes of the letter is opened and the assigned group of the participant is revealed.