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Study aim
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To evaluate the Effect of intravitreal triamcinolone during vitrectomy with epiretinal membrane peeling on the macular Optical coherent tomography characteristics.
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Design
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This is a prospective randomized controlled study of patients with idiopathic epiretinal membrane (ERM). Patients will be randomized in to two groups. Best corrected visual acuity (BCVA), Slit-lamp biomicroscopy, OCT and intraocular pressure (IOP) were measured for all patients before operation and 1, 3, 6 and 12 months after operation. The patients’ BCVAs will be converted to a logarithm of the minimal angle of resolution (logMAR) scale for analysis. A p-value <0.05 is considered to be significant.
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Settings and conduct
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pars plana vitrectomy and membrane peeling will be done in operation room in shiraz at khalili Hospital
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Participants/Inclusion and exclusion criteria
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women and men that have age between 50 to 80 years with following inclusion criteria:
• Patients with idiopathic epiretinal membrane (ERM), Decreased vision(BCVA:20/400-20/40) or meta-morphopsia and central foveal thickness more than 320 micron.
Exclusion criteria;
• Previous retinal surgery,
• retinal detachment,
• Age related macular degeneration,
• diabetic retinopathy,
• retinal vascular occlusion,
• uveitis,
• vitreous hemorrhage,
• trauma,
• ocular tumors,
• glaucoma,
• optic atrophy,
• fibrotic epiretinal membrane,
• macular pathologies other than ERM,
• significant cataract
• corneal opacity
• incomplete chart records
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Intervention groups
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Group1(N=20) included patients who underwent pars plana vitrectomy and membrane peeling without IVTA. Group 2 (N=20) included patients who underwent pars plana vitrectomy , membrane peeling and 1 mg intravitreal triamcinolone injection during operation.
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Main outcome variables
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central subfield thickness, best corrected visual acuity