Investigating the effectiveness of topical use of Black fat-tailed scorpion oil (Androctonus crassicauda ) on the pain of patient with chronic sciatica: A double-blind randomized clinical trial

Determining the effect of topical application of black broad tail scorpion oil on pain in patients with chronic sciatica

A parallel-group, double-blind, randomized clinical trial

The place of study is Tehran Traditional Medicine Research Center (Ahmadiyeh Health Center located on Khodaparast Street). The present study is a double-blind randomized clinical trial study. The study is conducted on 84 patients with chronic sciatica for 4 weeks. The study is double-blind (lack of knowledge of the patient and the researcher). How to use topical ointment: 3 times a day (morning, noon, night) each time in the size of 2 knuckles in the lower back area (from L1 down), buttock area to the middle of the back of the thigh on the side that hurts, for 4 weeks along with The massage will be rubbed. Also, due to compliance with ethical principles and not depriving patients of common treatments, study participants (both groups) can take diclofenac 25 mg tablets up to 2 times a day if they feel the need and severe pain.

-Entry criteria: 1-Patient with sciatica pain that lasts for at least 12 weeks 2-Age over 18 years 3-Pain equal to 4 or more based on VAS criteria 4-Not a candidate for surgery 5-Lack of any surgical history Exclusion criteria: 1-Pregnancy or breastfeeding 2-Creating severe side effects 3-Severe sensitivity to any of the drugs used in the study 4-Not agreeing to continue participating in the study 5-Intensification of the patient's pain and lack of control

The first group received medicated ointment containing scorpion oil and the second group received placebo ointment containing liquid paraffin.

Severity of leg and back pain with the Visual Analogue Scale

Random block method is used to divide people into two groups. The first group uses oleogel containing scorpion oil and placebo (oleogel without scorpion oil) is used on the second group. Simple Random Sampling (Simple Random Sampling) is one of the statistical sampling methods in which people in the community have an equal chance of being selected. In this method, each element of the desired statistical population has an equal chance to be selected. In this method, the needed people or objects are randomly selected from the list of the statistical population that is numbered and prepared for this purpose. According to the law of probability, the selected people should have the same characteristics as the society from which they were selected. The advantage of the authentication block method is the balance of the number of participants in two groups.

Medicines and placebo are in similar tubes with the same shape, color and smell. The specific codes are written by the pharmacist on the label of the medicine container and the placebo so that the patients and the researcher do not know the meaning of the codes.