Investigating the effect of 8 weeks of resistance training with blood flow restriction on muscle endurance, anaerobic and aerobic power and muscle damage indicators in Basiji students.
Determining the effect of 8 weeks of resistance training with blood flow restriction on muscular endurance, anaerobic and aerobic power, and muscle damage indices in Basiji students
Design
It is a basic applied research and in terms of data collection method, it is considered a type of intervention research with a control group. 34 subjects and random division.
Settings and conduct
Zanjan University Gymnasium and Zanjan University Physiology Laboratory.
Measurement of variables, then implementation of the protocol for 8 weeks, 2 sessions of front thigh and calf training per week, and measurement of variables again.
Participants/Inclusion and exclusion criteria
The statistical population of this study is all active Basij students at Zanjan University.
The research subjects are Basij students at Zanjan University who are studying.
The subjects should be free from any cardiovascular, neuromuscular, and skeletal disorders and should not use supplements, anti-inflammatory drugs, and anabolic steroids.
The subjects should be physically active.
Intervention groups
Intervention group: The intervention group will perform isometric exercises with blood flow restriction at an intensity of 30% MVC for two months.
Control group: The control group will perform isometric exercises without blood flow restriction at an intensity of 30% MVC for two months.
Main outcome variables
Quadriceps muscular endurance
Anaerobic power
Aerobic power
Indicators of muscle damage including creatine kinase and lactate dehydrogenase
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20250629066293N1
Registration date:2025-07-14, 1404/04/23
Registration timing:prospective
Last update:2025-07-14, 1404/04/23
Update count:0
Registration date
2025-07-14, 1404/04/23
Registrant information
Name
Hamidreza Salmanloo
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 24 3341 2675
Email address
hamidreza.salmanloo@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2025-07-23, 1404/05/01
Expected recruitment end date
2025-07-29, 1404/05/07
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Investigating the effect of 8 weeks of resistance training with blood flow restriction on muscle endurance, anaerobic and aerobic power and muscle damage indicators in Basiji students.
Public title
Investigating the effect of 8 weeks of resistance training with blood flow restriction on muscle endurance, anaerobic and aerobic power and muscle damage indicators in Basiji students.
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
The research subjects are Basiji students studying at Zanjan University.
Subjects should be free of any cardiovascular, neuromuscular, and skeletal disorders and should not use supplements, anti-inflammatory drugs, or anabolic steroids.
Subjects should be physically active.
Exclusion criteria:
Age
From 18 years old to 24 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
34
Randomization (investigator's opinion)
Randomized
Randomization description
34 students will be voluntarily selected and randomly divided into 2 groups (control and intervention) of 17 students using a random block design of 4.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Baqiyatullah Al-Azam (PBUH) Educational and Medical Center (Research Ethics Committee)
Street address
Department of Exercise Physiology, Health Research Institute, Baqiyatallah University of Medical Sciences, Sheikh Bahai South Street, Mulla Sadra Street, Vanak Square, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1435916471
Approval date
2025-05-26, 1404/03/05
Ethics committee reference number
IR.BMSU.BAQ.REC.1404.069
Health conditions studied
1
Description of health condition studied
Muscle damage indicators including creatine kinase and lactate dehydrogenase
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Lower body muscular endurance
Timepoint
At the beginning of the study and then for the second time 8 weeks later
Method of measurement
Using the front thigh machine at an intensity of 70% 1RM
2
Description
Anaerobic power
Timepoint
At the beginning of the study and then for the second time 8 weeks later
Method of measurement
30-second Ergojump test
3
Description
aerobic power
Timepoint
At the beginning of the study and then for the second time 8 weeks later
Method of measurement
Through the Cooper test
4
Description
Creatine kinase
Timepoint
At the beginning of the study and then for the second time 8 weeks later
Method of measurement
Through blood sampling and with the Pars Azmoun measurement kit
5
Description
Lactate dehydrogenase
Timepoint
At the beginning of the study and then for the second time 8 weeks later
Method of measurement
Through blood sampling and with the Pars Azmoun measurement kit
Secondary outcomes
empty
Intervention groups
1
Description
Intervention group: Front thigh and calf exercise with blood flow restriction using a cuff
Category
Rehabilitation
2
Description
Control group: Front thigh and calf training without restricting blood flow using a cuff
Category
Rehabilitation
Recruitment centers
1
Recruitment center
Name of recruitment center
University of Zanjan
Full name of responsible person
Hamidreza Salmanloo
Street address
Exercise Physiology Laboratory Building, University Boulevard, University of Zanjan, Zanjan, Iran
City
Zanjan
Province
Zanjan
Postal code
4537138791
Phone
+98 24 3305 1000
Email
hamidreza.salmanloo@gmail.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Bagheiat-allah University of Medical Sciences
Full name of responsible person
Behzad Bazgir
Street address
Department of Exercise Physiology, Health Research Institute, Baqiyatallah University of Medical Sciences, Sheikh Bahai South Street, Mulla Sadra Street, Vanak Square, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
Phone
+98 910 778 4079
Email
bazgirbehzad@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Bagheiat-allah University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
Bagheiat-allah University of Medical Sciences
Full name of responsible person
Hamidreza Salmanloo
Position
Student
Latest degree
Master
Other areas of specialty/work
Physiology
Street address
No. 32, Tohid2 Alley, Tohid Street, Nasr Town, Zanjan, Iran
City
Zanjan
Province
Zanjan
Postal code
4513777116
Phone
+98 24 3341 2675
Email
hamidreza.salmanloo@gmail.com
Person responsible for scientific inquiries
Contact
Name of organization / entity
Bagheiat-allah University of Medical Sciences
Full name of responsible person
Hamidreza Salmanloo
Position
Student
Latest degree
Master
Other areas of specialty/work
Physiology
Street address
No. 32, Tohid2 Alley, Tohid Street, Nasr Town, Zanjan, Iran
City
Zanjan
Province
Zanjan
Postal code
4513777116
Phone
+98 24 3341 2675
Email
hamidreza.salmanloo@gmail.com
Person responsible for updating data
Contact
Name of organization / entity
Bagheiat-allah University of Medical Sciences
Full name of responsible person
Hamidreza Salmanloo
Position
Student
Latest degree
Master
Other areas of specialty/work
Physiology
Street address
No. 32, Tohid Alley2, Tohid Street, Nasr Ave., Zanjan City, Iran
City
Zanjan
Province
Zanjan
Postal code
4513777116
Phone
009833412675
Email
hamidreza.salmanloo@gmail.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available