Comparison of the effect of coconut oil and pomegranate peel extract mouthwash on plaque-induced gingivitis with chlorhexidine mouthwash

Clinical study of the effect of mouthwash containing coconut oil and pomegranate peel extract on plaque-induced gingivitis.

The clinical trial has two groups of 20 people, randomized in a parallel, double-blind manner, and is in Phase 3 of the clinical trial. Randomization is done using a random number table. Random number tables are generated by computers that randomly arrange numbers.

Patients will be divided into 2 groups of 20 people based on the available indicators. Patients in the 2 groups will be matched in terms of gender. The double-blind cross-over method will be implemented; the patient and the relevant oral disease specialist will not know the contents of the bottle. The allocation of individuals to each group will remain hidden from the patient and the examining dentist until the end of the study. On the first day, scaling and brushing will be performed for all patients, and then the study group will use an oil-based mouthwash (10 ml) twice a day for 2 minutes for 14 days as a mouthwash, and the control group will use CHX twice a day for 14 days. On day 14, plaque index and BOP and gingival index are measured and recorded again.

Inclusion criteria: Presence of plaque and calculus on dental surfaces, presence of clinical signs of gingivitis, age range 18 to 65 years. Exclusion criteria: People with any systemic disease, pregnant and breastfeeding mothers, people who used mouthwash, received chemotherapy or antibiotic treatment, patients with poor motivation and/or poor cooperation, patients treated with calcium antagonists, cyclosporine and phenytoin, and patients who are allergic to coconut.

The intervention group uses the desired mouthwash, and the control group uses chlorhexidine mouthwash.

plaque index, gingival index, BOP

Before using the desired mouthwash, the periodontal status of the volunteers is checked and these volunteers are randomly assigned to one of the intervention and control groups using a random number table so that the distribution of oral health and disease status is the same between the two groups. The method of randomization is done using a random number table. Random number tables are prepared by computers that randomly arrange the numbers. These tables have random numbers in both rows and columns, which usually add up to 99 rows and columns, and the numbers in the rows and columns are placed next to each other and separated in five-digit blocks to facilitate their use.

Because the study is double-blind, except for the consultant supervisor as the third person in the study, none of the volunteers or students carrying out the project are aware of the placement of the study subject in the control or intervention group. In order to maintain confidentiality of the information for the individuals who were determined. The mouthwash container will be the same, Also, opaque containers will be used, so the contents of the containers will not be visible and no one other than the relevant professor will know how the mouthwash is distributed among the patients.