Protocol summary

Study aim
Comparing the effectiveness of mindfulness-based stress reduction therapy, compassion therapy, and emotion-focused therapy on aggression, functional flexibility, perceived stress, and cognitive avoidance in aggressive seventh-grade female students
Design
A controlled clinical trial with parallel groups, without blinding, randomized, on 80 patients. The rand function of Excel software will be used for randomization.
Settings and conduct
The statistical population of the present study consists of all aggressive seventh-grade female students in Ahvaz city who are studying in the 2025–2026 academic year. Initially, sampling will be performed using convenience sampling and according to the inclusion and exclusion criteria of the study. After selecting samples totaling 80 individuals, participants will be randomly assigned to 4 groups: “mindfulness-based stress reduction therapy,” “compassion-focused therapy,” “emotion-focused therapy,” and “wait-list.”
Participants/Inclusion and exclusion criteria
Inclusion criteria: seventh grade female students, scoring one standard deviation above the mean in aggression. Exclusion criteria: unwillingness to participate in the research, participation in other psychotherapy sessions.
Intervention groups
Intervention group 1: All individuals who will receive mindfulness-based stress reduction therapy. Intervention group 2: All individuals who will receive compassion therapy. Intervention group 3: All individuals who will receive emotion-focused therapy. Control group: All individuals who will receive no intervention.
Main outcome variables
Aggression, functional flexibility, perceived stress, cognitive avoidance

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20260425069159N1
Registration date: 2026-04-29, 1405/02/09
Registration timing: prospective

Last update: 2026-04-29, 1405/02/09
Update count: 0
Registration date
2026-04-29, 1405/02/09
Registrant information
Name
Azizeh Sharifi Naseri
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 61 3416 3452
Email address
zohreh.sharifi2018@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2026-05-15, 1405/02/25
Expected recruitment end date
2026-05-31, 1405/03/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparing the effectiveness of mindfulness-based stress reduction therapy, compassion therapy, and emotion-focused therapy on aggression, functional flexibility, perceived stress, and cognitive avoidance in aggressive seventh-grade female students
Public title
Investigating the effectiveness of mindfulness-based, compassion-based, and emotion-focused therapies on aggression and psychological indicators of adolescent students
Purpose
Education/Guidance
Inclusion/Exclusion criteria
Inclusion criteria:
Seventh grade female students Girls aged 12 to 13 years Obtaining a score one standard deviation above the average in aggression
Exclusion criteria:
Age
From 12 years old to 13 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 80
Randomization (investigator's opinion)
Randomized
Randomization description
The statistical population of the present study consists of all aggressive seventh-grade female students who are studying in the 2025–2026 academic year. In this type of effect-evaluation study, a two-stage approach is usually used: first, out of the four educational districts, two districts will be selected by simple random sampling (lottery), and then, by simple random sampling, 8 girls’ lower secondary schools will be selected from each district, and in the next stage, one seventh-grade class from each school will be selected. In the sampling stage, a convenience sampling method will be used. In this way, after the students complete the aggression checklist, those whose scores on this checklist are one standard deviation above the mean, and for whom, in a clinical interview conducted by one of the clinical psychology specialists, a final diagnosis of aggression has been made, will be selected as students with aggression. After selecting the samples up to a total of 80 participants, based on the inclusion and exclusion criteria of the study, the participants will be randomly assigned to four groups: “mindfulness-based stress reduction therapy” (intervention group 1), “compassion-focused therapy” (intervention group 2), “emotion-focused therapy” (intervention group 3), and “wait-list” (control group). Randomization will be performed using variable-size random blocks (of 4 and 6 participants) by an independent statistician who is not involved in the implementation process. The random allocation list will be generated using the RAND function in Excel software and then placed in opaque, sealed, and numbered envelopes so that the researcher and participants are unaware of the allocation sequence (allocation concealment). Opening the envelopes and becoming aware of the allocation group will only be done at the time of each participant’s entry into the study. To ensure equality of baseline variables (such as anxiety level and age), their distribution in the two groups will be examined at the stage of statistical analysis.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Islamic Azad University of Ahvaz Branch
Street address
Opposite Keshavarz Street, Farhang Shahr, Golestan Highway
City
Ahvaz
Province
Khouzestan
Postal code
6134937333
Approval date
2026-02-18, 1404/11/29
Ethics committee reference number
IR.IAU.AHVAZ.REC.1405.002

Health conditions studied

1

Description of health condition studied
aggression
ICD-10 code
R45.6
ICD-10 code description
Violent behavior

Primary outcomes

1

Description
Aggression
Timepoint
1. Pre-test (before the start of the intervention) 2. Post-test (immediately after the end of the intervention period) 3. One-month follow-up after the intervention
Method of measurement
The method of measurement will be using the aggression inventory of Zahedifar et al. (1379).

2

Description
Functional Flexibility
Timepoint
1. Pre-test (before the start of the intervention) 2. Post-test (immediately after the end of the intervention period) 3. One-month follow-up after the intervention
Method of measurement
The measurement method will be using the Connor and Davidson (2003) Functional Flexibility Questionnaire.

3

Description
Perceived Stress
Timepoint
1. Pre-test (before the start of the intervention) 2. Post-test (immediately after the end of the intervention period) 3. One-month follow-up after the intervention
Method of measurement
The measurement method will be using the Cohen et al. (1983) questionnaire.

4

Description
Cognitive Avoidance
Timepoint
1. Pre-test (before the start of the intervention) 2. Post-test (immediately after the end of the intervention period) 3. One-month follow-up after the intervention
Method of measurement
The measurement method will be the Sexton and Dugas (2008) Cognitive Avoidance Questionnaire.

Secondary outcomes

empty

Intervention groups

1

Description
Intervention Group 1: Mindfulness-Based Stress Reduction Therapy. Duration of each session: 90 minutes. Total number of sessions: 8 sessions. Session frequency: Twice a week. Therapeutic tools used: Guided mindfulness exercises (e.g., body scan, breathing meditation, gentle yoga), training in mindfulness principles in daily life, and group discussions to share experiences. Content of sessions: Session 1: Introduction to mindfulness, body scan practice, fundamentals of stress. Session 2: Focus on breathing, awareness of thoughts and feelings without judgment. Session 3: Body awareness, mindfulness-based gentle yoga. Session 4: Dealing with difficult thoughts, observing thoughts as mental events. Session 5: Awareness of stress reactions, emotion management. Session 6: Mind-body connection, acceptance of unpleasant experiences. Session 7: Self-care, developing interpersonal relationships with mindfulness. Session 8: Conclusion, integrating mindfulness into life, planning for the future, and conducting the post-test.
Category
Treatment - Other

2

Description
Intervention Group 2: Compassion-Focused Therapy. Duration of each session: 90 minutes. Total number of sessions: 8 sessions. Session frequency: Twice a week.Therapeutic tools used: Guided talk therapy, mindfulness exercises (with a focus on compassion), self-compassion imagery exercises, compassion for others imagery exercises, and emotion regulation techniques. Content of sessions: Session 1: Introduction to the concept of compassion, differentiating compassion from pity, theoretical foundations of Compassion-Focused Therapy, and pre-test administration. Session 2: Identifying dysfunctional thought and behavioral patterns towards oneself, understanding the roots of self-criticism. Session 3: Practicing self-compassion imagery, using a soothing breath technique for relaxation. Session 4: Mindfulness practice for better emotional understanding, expressing empathy towards oneself and others. Session 5: Practicing writing a compassionate letter to oneself, healthy emotional release. Session 6: Pathologizing internal and external barriers to compassion (such as fear, aversion), examining factors that reduce compassion. Session 7: Teaching methods to cope with compassion barriers, practicing deep relaxation techniques. Session 8: Summarizing interventions, providing final suggestions for consistent compassion practice, administering the post-test, and scheduling a follow-up appointment.
Category
Treatment - Other

3

Description
Intervention Group 3: Emotion-Focused Therapy: Duration of each session: 90 minutes. Total number of sessions: 8 sessions. Session frequency: Twice a week. Therapeutic tools used: Emotion-focused techniques, guided talk therapy for deep exploration of emotions, experiential exercises for processing and expressing emotions, techniques for establishing safe and intimate connections, and emotion regulation exercises within the context of relationships. Session content: Session 1: Introduction to the core concepts of Emotion-Focused Therapy, understanding primary and secondary emotions, and conducting the pre-test. Session 2: Exploring and identifying dysfunctional interaction patterns and the emotions associated with them. Session 3: Focusing on emotions hidden behind defensive behaviors, and creating a safe space for emotional expression. Session 4: Experiential processing of difficult emotions, and using experiential techniques for deeper understanding. Session 5: Reconstructing interactions with a focus on establishing secure attachment, and expressing needs and fears. Session 6: Strengthening emotional communication skills, and practicing the expression of compassion and mutual understanding. Session 7: Consolidating the changes made, and practicing conflict management with an emotion-focused approach. Session 8: Summarizing the interventions, providing strategies for maintaining and continuing healthy emotional connection, conducting the post-test, and scheduling follow-up.
Category
Treatment - Other

4

Description
Control group: The control group will not receive any type of intervention during the implementation of the research; however, in order to prevent threats to the internal validity of the study, such as compensatory rivalry of the control group or morale undermining, after data collection, they will receive the compassion-based therapy intervention.
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Girls' Junior High Schools in Ahvaz
Full name of responsible person
Azizeh Sharifi Naseri
Street address
No. 708, Mordad 3 St, Naft town
City
Ahvaz
Province
Khouzestan
Postal code
6165745439
Phone
+98 61 3416 3452
Email
zohreh.sharifi2018@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Islamic Azad University
Full name of responsible person
Aslan Egdarnezhad
Street address
Opposite Keshavarz Street, Farhang Shahr, Golestan Highway
City
Ahvaz
Province
Khouzestan
Postal code
6134937333
Phone
+98 61 3334 8421
Email
a_eigder@ymail.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University
Proportion provided by this source
100
Public or private sector
Private
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Azizeh Sharifi Naseri
Position
Ph.D. student
Latest degree
Master
Other areas of specialty/work
Psychology
Street address
No. 708, Mordad 3 St, Naft town
City
Ahvaz
Province
Khouzestan
Postal code
6165745439
Phone
+98 61 3416 3452
Email
zohreh.sharifi2018@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Azizeh Sharifi Naseri
Position
Ph.D. student
Latest degree
Master
Other areas of specialty/work
Psychology
Street address
No. 708, Mordad 3 St, Naft town
City
Ahvaz
Province
Khouzestan
Postal code
6165745439
Phone
+98 61 3416 3452
Email
zohreh.sharifi2018@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Azizeh Sharifi Naseri
Position
Ph.D. student
Latest degree
Master
Other areas of specialty/work
Psychology
Street address
No. 708, Mordad 3 St, Naft town
City
Ahvaz
Province
Khouzestan
Postal code
6165745439
Phone
+98 61 3416 3452
Email
zohreh.sharifi2018@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Not applicable
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Not applicable
Data Dictionary
Not applicable
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