Study aim: The objective of this study is to compare the efficacy of the new anti-epileptic drug lacosamide when compared with conventional treatment with topiramate for the treatment of young adults with chronic migraine Design: Quasi experimental interventional study Settings and conduct: Double blinded with the doctor and patient unaware of the study protocol with the doctor advising the interventional drug to the patient in sealed envelopes from the department Participants/Inclusion and exclusion criteria: All male and female patients aged 18-30 diagnosed with migraine according to the ICHD 3 criteria and having chronic migraine will be included Patients with diabetes and hypertension or critical respiratory, renal or cardiac disease, patients with allergy to lacosamide or topiramate and patients unwilling to be included in the study will be excluded Intervention groups: Two Groups Group L receiving Oral Lacosamide 150 mg twice a day Group T recieving Oral Topiramate 50 mg twice a day Main outcome variables: Frequency of acute attacks in the following three months of therapy and improvement seen by standard Chronic headache quality of life questionnaire

Study aim: : The objective of this study is to compare and observe the post-operative analgesic efficacy of ultrasound guided transversalis fascia plane (TFPB) block when compared with anterior quadratus lumborum (QL) block in patients undergoing caesarian section. Design: Prospective observational study Settings and conduct: Prospective observational study Participants/Inclusion and exclusion criteria: incluson criteria included all ASA-I and II female patients presenting for elective caesarian with a gestational age of more than 38 weeks to be done by Pfannenstiel incision under general anesthesia. Exclusion criteria excluded patients with metastatic disease, major cardiac or respiratory disease, low ejection fraction, post chemotherapy, major coagulopathy and unwilling to be included in the study Intervention groups: Both blocks were done bilaterally under ultrasound guidance following the standard aseptic techniques and protocols furnished by NYSORA at the end of surgery under general anesthesia. Primary variables measured were mean total 24-hour morphine consumption and median scores on the NRS scale at 3-, 6-, 12- and 24-hours interval Main outcome variables: post operative analgesia in patients undergoing cesarian section

Study aim: Compare the analgesic efficacy of magnesium sulfate versus lignocaine with intravenous acetaminophen in asthmatic patients undergoing laparoscopic cholecystectomy. Design: The patients were Group into M (n=55) receiving IV MgSO4 and IV Acetaminophen and Group L (n=55) IV Lignocaine with IV Acetaminophen. Variables measured were per-operative mean heart rate, mean arterial pressure, time to first rescue analgesia, total dose of analgesia required in the next 24 hours post-surgery, and median pain scores at 1-, 3- and 6-hour intervals. Settings and conduct: This quasi-experimental study was carried out at the Department of Anesthesiology, Combined Military Hospital, Rawalpindi from Jun 2023-Dec 2023. Participants/Inclusion and exclusion criteria: Inclusion criteria: Patient undergoing laparoscopic cholecystectomy which included all ASA-I and II patients diagnosed with asthma by spirometry pre- and post-bronchodilator therapy. Exclusion criteria: included patients with major cardiac or respiratory disease, low ejection fraction, unoptimized for hypertension or diabetes, patients with cholecystitis, patients allergic to acetaminophen, MgSO4, lignocaine or nalbuphine, patient with history of asthma exacerbation requiring admission in the last 8 weeks, patients on oral or intravenous steroids for asthma and patients unwilling to be included in the study. Intervention groups: patients were divided into two groups. Patients in Group M received intravenous MgSO4 with intravenous acetaminophen. Patients in Group L received intravenous lignocaine with intravenous acetaminophen. Main outcome variables: heart rate, mean arterial pressure, time to first rescue analgesia, total dose of analgesia required in the next 24 hours post-surgery, and median pain scores at 1-, 3- and 6-hour intervals.

Study aim: EFFECTS OF PILATES VS CORE STABILIZATION EXERCISES ON PULMONARY FUNCTIONS AND CHEST WALL EXPANSION IN COPD PATIENTS Design: Two parallel group , single blinded, randomized control trial with pre and post assessment Settings and conduct: Pulmonology Ward District Headquarter Hospital Narowal Participants/Inclusion and exclusion criteria: Inclusion criteria Patients with stable COPD Male & female age >18 years Able to walk independently Ability to perform voluntary given exercise program Did not participate in any training program during the last six months Exclusion criteria Unstable COPD >4 months hospital admissions due to COPD during last 1 year cognitive impairments  progressive neuromuscular disease Spinal cord Injuries or severe orthopedic problems cardiovascular Intervention groups: Group A: will be treated by Pilates exercises with deep breathing Group B: will be treated by core stabilization exercises with deep breathing Main outcome variables: Assessment of pulmonary functions by using spirometer. tape measurement for chest wall expansion.

Study aim: To find out Effects of exercise training with whole-body electric muscle stimulation on cardiorespiratory perceived exertion, dyspnea and pulmonary function test in obese females Design: Two parallel group , single blinded, randomized control trial with pre and post assessment Settings and conduct: Pro EMS Fitness & Rehabilitation Center Participants/Inclusion and exclusion criteria: 1. Age 25- 40 yrs 2. Obese Females 3. Hypothyroid 4. BMI(30-39.99) 5. Ability to perform physical activity voluntarily 6. Dyspnea Exclusion Criteria: 1. Physical Inactivity 2. Skin Allergies 3. Abdomen or groin hernia tuberculosis 4. Cancer 5. Neurologic disturbances 6. Bleeding tendencies 7. Reported injuries (i.e. hip, abdomen, groin and hernia) 8. Diseases (i.e. epilepsy, cardiac arrhythmia) Intervention groups: Standardized EMS training program along with obese females Main outcome variables: Borg Scale 6-Min Walk Test Spirometer

Study aim: This study investigates the effect of virtual reality (VR) intervention in improving balance, postural control and stability in acute and sub acute stroke patients Design: Non-probability consecutive sampling Settings and conduct: Allied hospital Faisalabad Participants/Inclusion and exclusion criteria: Inclusion criteria • Willing to give consent • Patients having age between 45 to 60 years • Both male and female • Mini mental scale more than 18 score • Burg Balance Scale score less than 20 Exclusion Criteria • Recurrent stroke episodes • Any other neurological conditions that causes balance disturbs that is Azheimer, parkinsons, dementia • Malignancy, infectious disease • Any surgery within last 6 months • Chronic stroke patients Intervention groups: Group A recieved an active control group will receive baseline treatment that is Functional electrical stimulation and Range of motion exercises for balance. Range of motion exercises are Ankle movements, stand tall,feet together, side steps, Hip abduction, Heel rises, weight shift, and leg stance, balance walking. Each exercises performed with the repitions of 10 reps, 5 sets. Functional electrical stimulation used for the stimulation and improving balance. FES deilievered with 0.3-ms pulses at 30 HZ with the maximum tolerance of intensity 20-30 mA in acute stage Goup B received protocol which includes virtual reality along with baseline treatment. A total of 18 sessions (3 alternate sessions per week or 45 min each) performed on the participants in 40 minute session Main outcome variables: Balance Berg Scale Postural assessment scale for stroke

Study aim: The objectives are to enhance gaze stability through the application of gaze stabilization exercises and Cawthorne Cooksey exercises also to study and compare the effect of Gaze stabilization exercises and Cawthorne Cooksey exercises on Craniovertebral angle, Thoracic angle, Vestibular ocular reflex, Cervical ranges. Design: Simple random sampling. Settings and conduct: The University of Faisalabad. Participants/Inclusion and exclusion criteria: Inclusion criteria • Participants willing to give consent • IT students • Both genders • Age: 19-25 years • Screen time 6-8 hours • VOR(+) • Craniovertebral angle 50°-53° • Thoracic angle 300-500 Exclusion criteria • Uncooperative participants • No other neurological disorder • History of ear infection • History of migraine • History of dizziness, vertigo • Subjects with history of head injury • Subjects with ADHD Intervention groups: Group A The participants of experimental group A will perform Gaze stabilization exercises as treatment approach for 3 weeks, 3 sessions per week and 3 times a day. Group B The participants of experimental group B will perform Cawthorne Cooksey exercises as a treatment protocol for 1 minute thrice a day (total 3 minutes per day) on alternate days for 3 weeks, 3 sessions per week and 3 times a day. Main outcome variables: Goniometer Inclinometer

Study aim: The study aims to see the effect of sodium bicarbonate supplementation on the nutritional status of patients on maintenance hemodialysis Design: Single-centre, randomized clinical trial Settings and conduct: This single-center clinical trial will be conducted at the Pak Emirates Military Hospital (Dialysis Unit). Patients will be randomized to either a control or study group after consent. Hand grip strength, and triceps skinfold thickness along with serum bicarbonate, albumin, creatinine, and hemoglobin will be noted at baseline, 2, 4, 6 and 12 weeks.. Participants/Inclusion and exclusion criteria: Individuals from either gender who were > 18 years of age on twice weekly maintenance hemodialysis for more than 6 months, able to comply with study instructions, and having serum bicarbonate levels ≤23mmol/L were included in the study. Individuals having an active infection, unstable heart disease, congestive heart failure, limb amputation and renal tubular acidosis were excluded from the study. Moreover, patients on bisphosphonate therapy, and calcium or sodium bicarbonate therapy were also excluded. Intervention groups: The participants were divided into 2 groups. The control group was not given any medication while the Study group was given tablet Sodium Bicarbonate 600mg three times a day orally. Main outcome variables: Changes in hand grip strength, triceps skinfold thickness, serum bicarbonate, serum albumin, and hemoglobin will be noted.

Study aim: To compare the efficacy of pregabalin and sertraline in treating uremic pruritus Design: Randomized clinical trial Settings and conduct: This single-center clinical trial would be conducted at the Pak Emirates Military Hospital (Dialysis Unit). All patients to provide consent. Patients to be randomized to receive either Pregabalin or Sertraline. Urdu version of the 5-D Itch Scale would be self-administered to assess severity of itching at baseline, and at 6 weeks post commencement of treatment. Participants/Inclusion and exclusion criteria: Patients of both genders having age ≥19 years, on twice weekly HD for ESRD for at least six months, and having UP for at least six weeks, were included in this study. Exclusion criteria included dermatological or systemic diseases associated with pruritis, mental health issues affecting the ability to respond to the 5-D Itch Scale, and patients on a thrice-a-week HD schedule. Moreover, individuals already on some treatment for UP were generally excluded, except for patients on oral anti-histamines, for whom there was a washout period of two weeks before participation in this study Intervention groups: The Pregabalin group would be given Pregabalin 75mg once a day orlly, while Sertraline Group would be given sertraline 50mg once a day orally. Main outcome variables: Change in the severity of pruritus after six weeks of intervention.

Study aim: To Compare Efficacy of Intravenous versus Intramuscular Meglumine Antimoniate in Treatment of Cutaneous Leishmaniasis Design: Clinical trial which is parallel group, double blind, randomized, phase 3 trial. Settings and conduct: Dermatology Department, CMH Quetta Participants/Inclusion and exclusion criteria: INCLUSION CRITERIA: Patients with biopsy proven cutaneous leishmaniasis and fulfilling the criteria for parenteral treatment with injection meglumine antimoniate. EXCLUSION CRITERIA: Patients of cutaneous leishmaniasis allergic to antimonial ,having comorbidities (diabetes, hypertension,chronic liver disease,chronic kidney disease, ),baseline ECG abnormality/heart disease,pregnant and breastfeeding women. Intervention groups: Intervention group A: Patients were given drug via Intravenous route. The drug should be given diluted in 50–200 ml of 5% glucose solution over 30–60 minutes in ICU/HDU with cardiac monitoring. Intervention group B: Patients were given drug via Intramuscular route. If the volume of injection exceeds 10 ml, it should be divided into two doses: one in each buttock or thigh. Main outcome variables: Clinical Response

Study aim: Aim of the study to determined exercises management for pain and forward head posture in patient with cervical spondylosis Design: Randomized control trail study Settings and conduct: The current study carried out in WAPDA teaching hospital in physical therapy department Participants/Inclusion and exclusion criteria: The inclusion criteria of study includes both male and female, aged 40-60 year, no pervious history of trauma, surgery and diagnosed patients by orthopedic, pain is not more than 8 at VAS. Pregnant women, Pain is more than 8 at VAS, history of previous cervical surgery, vertebral compression fracture, history of malignancy, rheumatoid disorder and other systemic problems were excluded. Intervention groups: Group A or Interventional group will received cervical isometric and postural corrected exercises with shoulder dynamics exercises 4 session per week for 6 week. GROUP B or Control group will received cervical isometric and postural corrected exercises 4 session per week for 6 week. Main outcome variables: Pain and forehead posture

Study aim: To check the effects of knee and hip muscles strengthening and stretching exercises in patellofemoral pain syndrome Design: Experimental Settings and conduct: District Head Quarter Hospital Study will be conduct in Orthopedic department Participants/Inclusion and exclusion criteria: inclusion criteria : sedentary females with age of 21-50 Exclusion Criteria: Female who are pregnant or suffering with neurological disorders or any surgery of effected limb Intervention groups: Group A will receive knee and hip muscle strengthening exercises Group B will receive knee and hip muscle stretching exercises Main outcome variables: pain Functional status

Study aim: To evaluate and compare the effects of muscle energy techniques (post isometric relaxation and reciprocal inhibition) to improve hamstring flexibility, anterior pelvic tilt, functional status and pain with knee osteoarthritis Design: Single Blinded Randomized Clinical Trial Settings and conduct: District Head Quarter (DHQ) hospital Allied hospital Madinah teaching hospital Participants/Inclusion and exclusion criteria: Inclusion criteria: Age : 45-60 years old Gender: Both Pain : mild to moderate osteoarthritis: grade II and III Womac (The Western Ontario and McMaster Universities Arthritis Index) scoring: 65-75 Active knee extension test: 15-20 degree. Exclusion criteria: Patients with low back issue Patients with previous history of infection, trauma, implant and surgery of affected limb Intervention groups: Group A ( Post isometric relaxation) Group B ( Reciprocal Inhibition) Main outcome variables: Hamstring flexibility - Anterior pelvic tilt - Functional status - Pain

Study aim: Prevention of preeclampsia by taking vitamin D supplements Design: Two-arm parallel group randomised trial with blinding Settings and conduct: Gynecology department unit III of Nishtar Hospital, Multan Participants/Inclusion and exclusion criteria: Patients who presented at the outpatient department of the hospital for prenatal care and had a previous history of preeclampsia during a previous pregnancy were included. Patients with renal insufficiency, cardiac disease, and hypertension before pregnancy, lack of confidence in cooperation, immunological disease and leaving during study were excluded Intervention groups: In the intervention group, patients were given 50000 IU capsules of vitamin D3 once every 2 weeks. Main outcome variables: Occurrence of Preeclampsia Type of delivery Abortion rate

Study aim: To compare the efficacy of Aripiprazole versus Risperidone augmentation of SSRIs for in the treatment of resistant OCD. Design: Two arm parallel group randomised trial, single blinded Settings and conduct: Lahore general hospital Participants/Inclusion and exclusion criteria: Inclusion Criteria:  Patients of age 16-65 years of either gender  Patients diagnosed with obsessive compulsive disorder (as per operational definition) with Y-BOCS score ≥16. Exclusion Criteria:  Pregnant females.  Patient allergic to trial drugs.  Patient having an organic cause for their symptoms.  Patient with comorbid conditions that aggravate the condition or develop depression and anxiety. Intervention groups: In group A, patients will be given Aripiprazole started with a 2.5 mg daily dose and will be gradually increased to 10 mg daily by the end of the second week. In group B, Risperidone initiated with a 1 mg daily dose and was gradually increased to 2 mg daily by the end of the second week. Main outcome variables: Y-BOCS SCORE

Study aim: To determine the effect of vitamin D supplementation on serum total cholesterol, triglycerides, low density lipoproteins and high density lipoproteins among patients with metabolic syndrome Design: Two arm parallel group randomized trial without any blinding in outcome assessment. Randomization sequences would be generated online and concealed using opaque envelopes. There will be a minimum of 74 patients, equally divided into the two groups. Settings and conduct: This trial would be done in the outdoor medical clinic of Pak Emirate Military Hospital. Patients would be selected by non-convenience probability sampling technique and included in the study subject to provision of consent. They would be randomized into two groups using computer generated sequences. Allocation concealment would be done using opaque envelopes. Patients in the intervention arm would receive a single dose of oral Vitamin D as stated above, in addition to usual care. Those in the control arm would receive the usual standard care only. Participants/Inclusion and exclusion criteria: Inclusion criteria: Patients satisfying National Cholesterol Education Program Adult Treatment Panel III criteria for metabolic syndrome Exclusion criteria: Current use of lipid lowering drugs Use of vitamin D supplements in the last 6 months Hypothyroidism Pregnancy Chronic kidney disease stages 3- 5 Cholestasis Nephrotic syndrome Intervention groups: Patients would be given two doses of oral Vitamin D 200000 IU to be taken orally at weeks 0 and 4, in addition to usual medications. Patients in the control group would not be given Vitamin D supplements. They would just receive their usual medications Main outcome variables: Changes in serum total cholesterol, triglycerides, high density lipoproteins and low density lipoproteins levels

Study aim: Primary Objective: To evaluate the effects of arm crank exercises on Dyspnea, Left Ventricular Ejection Fraction and exercise capacity in patients with angioplasty. Secondary Objective: To evaluate the effects of arm crank exercises on hemodynamic parameters (heart rate and blood pressure) Design: Randomized Controlled Trial Settings and conduct: Cheema Hospital Gujranwala Participants/Inclusion and exclusion criteria: Inclusion Criteria:  Patients having planned angioplasty  Both male and female patients  Post extubation  Signed written informed consent  Age 40-60years(15) Exclusion Criteria:  PCI to nonnative vessel  Implantation of >3 stents  Evidence of thrombus  Presence of infection  Ejection fraction <30%(16) Intervention groups: Group A: Patients will be treated by standard angioplasty medical protocol. Group B: Patients will be treated by using arm ergometer. Main outcome variables: Dyspnea Left Ventricular Ejection Fraction Exercise capacity Hemodynamic parameters (heart rate and blood pressure)

Study aim: The aim of this study is to find the potential benefits of these exercises in promoting overall physical health and functional recovery in individuals who have experienced a stroke. Design: Randomized Clinical Trial Settings and conduct: Tariq Hospital Lahore Participants/Inclusion and exclusion criteria: Inclusion Criteria • Age between 35-55 years • Both male and female gender • History of Ischemic Stroke • Patient with Hemiplegia • Patient 6 months after stroke consider chronic • Berg balance scale value greater than 45 • Hemodynamically stable • Stable medical and Musculoskelton condition allowing physical activity Exclusion Criteria • Stroke patient with flaccid paralysis • Cognitive Impairment • Patient with cardiothoracic surgery • Uncontrolled hypertension • Sever joints disease such as OA, RA and Gout. • Any other neurological disease • Chronic pulmonary disease like COPD Intervention groups: Group A: Experimental Group will receive Calisthenics Exercises. Group B: Experiment Group will receive Circuit Tanning.. Main outcome variables: Cardiorespiratory Fitness Chest Expansion Pulmonary Functions

Study aim: The previous literature shows lack of studies specifically comparing the effects of routine physiotherapy with and without FDM on pain, functional disability, and ROM in patients with CLBP. Understanding the effects of routine physiotherapy with and without FDM on pain, functional disability, and ROM in patients with CLBP can provide valuable insights into the effectiveness of these interventions and guide evidence-based clinical decision-making. The findings of this study may have implications for the development of more effective treatment protocols for chronic low back pain. Design: Parallel study with conveniet sampling technique . It is a Randomized Control Trial with single blinding of group division. Data will be collected for 6-9 months after approval Settings and conduct: Data will be collected from DHQ hospital Muzaffargarh Participants/Inclusion and exclusion criteria: Inclusion criteria: low back pain of more than 3 months; age 30-65 years old; both male and female. Exclusion criteria: low back pain associated with any structural deformity e.g scoliosis; osteoporosis; spinal fracture; LBP with Radicular symptoms; cauda equina syndrome. Intervention groups: Fascial distortion model will be implied as Intervention group. There will be a three-week treatment plan with total 6 sessions each group that can be divided into baseline, first week second week and third week, comparing the two interventions. Main outcome variables: Pain

Study aim: The purpose of the current study will be to assess the impact of cervical traction and MST on pain, functional disability and grip strength in subjects suffering from cervical radiculopathy. Design: It is a randomized controlled trial with double blinding of subjects. Data will be collected for 6-9 months after approval Settings and conduct: Data will be collected from Physical therapy department of Ibn e siena Hospital, Multan Participants/Inclusion and exclusion criteria: INCLUSION CRITERIA Both male and female individuals aged 30-50 years, Individuals with upper-limb pain that had been radiating from their neck for more than three weeks, The clinical prediction rule will be used to diagnose the participants which includes four elements out of which, presence of three elements confirm Cervical Radiculopathy diagnosis. EXCLUSION CRITERIA History of previous cervical or thoracic spine injury, Recent fracture or surgery in and around the shoulder, Any systemic disease, Any comorbid factors, Pregnancy Intervention groups: Patients will be randomly allocated to two groups Patients in both groups will receive conventional therapy. Group A will be treated with cervical traction. Group B will be treated with Myokinetic Stretching technique, which consists of active and passive stretches with myofascial release (MFR) Main outcome variables: Pain and functional disability

Study aim: The objective of this study is to compare the differences in postoperative complication, surgical procedure length, duration of hospitalization, duration of return to work and relapse frequency between the enhanced view totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP) approaches for inguinal hernia repairs. Design: Randomized control trial, non blinded, with parallel group design of 50 patient for suspected period of 6 months after approval of RCT. Settings and conduct: This study was conducted in Sheikh Zayed Hospital Rahim Yar khan. The study was not blinded. The patient were told about the surgery. The surgery was done after informed written consent. Participants/Inclusion and exclusion criteria: Patient with age 15 and 60 year of any gender were included. Patient with reducible inguinal hernia were included. Patient having previous history of mildline surgery and with recurrent inguinal hernia were excluded. Patient with strangulated and obstructed hernia were excluded. Intervention groups: Two groups wer made. In one group A patients were undergone trans abdominal preperitoneal hernia repair (TAPP) and in group B total extraperitoneal hernia repair (e-TEP) was done after informed written consent. Main outcome variables: Postoperative complication, Surgical procedure length, Duration of hospitalization, Duration of return to work and relapse frequency

Study aim: To compare the immediate effects of Muscle energy technique (post isometric relaxation) and primal reflex release technique in hamstring tightness. To check the improvement in ROM, pain and flexibility in hamstrings in the people suffering from hamstring tightness Design: Randomized, superiority, paralell group trial, single blinded. randomised was done through lottery method. Settings and conduct: the trial was conducted in The University of Faisalabad. it was single blinded trial and only participants were blinded. Participants/Inclusion and exclusion criteria: inclusion criteria: 1- Age group between 17 to 25 years healthy subjects (females). 2- Should have long sitting in daily routine 3- NPRS scale 3 or more. 4- Sit and reach score below 19 exclusion criteria: 1- history of lower extremity injury in past 3 month 2- motor neuron lesions 3- pregnancy 4- open wounds 5- systemic illness history Intervention groups: Subjects were randomly allocated in two groups by using lottery ticket method. Pre values were recorded before the session. Moist hot pack will be used as baseline treatment. Group A received Muscle Energy Technique and group B received Primal Reflex Release Technique. Post values were recorded after the session Main outcome variables: • Rom • Pain • Flexibility of hamstrings

Study aim: To compare the effects of post isometric relaxation and active release technique on calf muscles tightness in young females. Design: A Randomized Clinical Trial with two parallel groups, a single- blinded study of third phase with 15 patients in group, which is 30 in total. Settings and conduct: Subjects were randomly selected from outdoor Patient Department OPD and following clinical setup. Allied Hospital Faisalabad. Patients were kept unaware about which group they allocated. Participants/Inclusion and exclusion criteria: • Age group 20-40 • Had symptoms of pain, tightness and functional loss. • Patient with calf pain VAS moderate(4-7) • Lower extremity functional scale functional disability due to calf tightness • Weight bearing wall lunge test positive in patients • Ankle fracture. • Pregnancy. • Deep Vein Thrombosis. • Medication like cholesterol lowering drugs. • Compartment syndrome. • Radiating pain. • Sports related injury Intervention groups: Group A of Muscle Energy Technique Group B Active Release Technique Main outcome variables: 1. Pain 2. Ankle Range Of Motion 3. Functional Disability

Study aim: To decrease the patient load in the resource limited setups by decreasing the mean hospital stay of the patients admitted with TTN. Design: Randomized, Concealed, doub;e blinded study Settings and conduct: being conducted in CMH Bahawalpur. it was blinded by the study designer, consultant pediatrician Participants/Inclusion and exclusion criteria: Inclusion criteria: Inclusion criteria included all full term and late preterm infants diagnosed with Transient tachypnea of newborn of both sex born via either caesarian section and spontaneous vaginal delivery. Exclusion criteria: Exclusion criteria included. Patients of respiratory distress but not under umbrella of Transient tachypnea of newborn. Diagnosis was made on the basis of detailed examination, CXR, blood glucose levels, Complete blood count and C-reactive protein. Patients of the Diseases that were excluded were the cases of Meconium aspiration (Cord and skin stained with meconium , Chest x-rays showing lung opacities and hyperinflation of lungs), Pneumonia (consolidations), Neonatal Respiratory Distress Syndrome(NRDS) (Air bronchograms on CXR), , Neonatal Sepsis(early onset) (positive C reactive protein), Hypoglycemia (BSR less than 54mg/dl respectively), Polycythemia(Hematocrit greater than 60%), Heart Murmur ( via auscultation ) and Tachycardia (heart rate greater than 180/min). Intervention groups: I/V furosemide was given. Main outcome variables: to try to decrease the mean hospital stay of the patients admitted with TTN.

Study aim: The study will be conducted to investigate the best technique in increasing flexibility in post burn contractures in elbow joint Design: This study will be a Randomized clinical trial with a sample size of 60 burn patients with contractures who had decreased muscle flexibility as a result of partial thickness burn. Data will be selected through convenient sampling from the Burn Unit Ward of Allied Hospital, Faisalabad. However, Informed consent will be taken from participants. Palpation, Visual analogue scale and goniometer will be used for pre and post-assessment. Sixty patients will be divided into two groups, thirty in each group. Group (1): received Muscle Energy Technique (MET), Group (2): received 20 sec of static stretching exercise. Measurements of elbow extension range of motion were conducted before treatment, post 5 days of treatment, and after 8 days of treatment. Settings and conduct: Burn Unit Ward of Allied Hospital, Faisalabad Participants/Inclusion and exclusion criteria: Inclusion criteria: Age 20-50 years Gender (both) 2nd degree deep and 3rd degree burns in elbow Patients with unilateral tight elbow flexors Superficial skin grafted individual Subjects not involved in any exercise activity at the start of the study Exclusion criteria: history of serious pathology (e.g. malignancy, inflammatory disorder, infection) history of cervical radiculopathy hand deformities fractured or dislocated elbow Intervention groups: Sixty patients will be divided into two groups, thirty in each group. Group (1): received Muscle Energy Technique (MET), Group (2): received 20 sec of static stretching exercise. Main outcome variables: Pain; Range of motion