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Study aim:
This clinical trial before and after study is carried out with the aim of evaluating the prophylactic effect of Levetiracetam on pediatric migraine and its comparison with propranolol
Design:
A clinical trial with control group, with parallel groups, randomized and 30 patients in each group
Settings and conduct:
The study will be performed in Neurology clinic of Bouali Hospital of Sari and the patients are non-blinded.
Participants/Inclusion and exclusion criteria:
Age 5 to 15 years, migraine attacks more than once a week causing the child's disability (PedMIDAS score > 20) and headache prophylaxis is required in the child
Intervention groups:
In the intervention group, the Levetirastam tablet with brand name of Levebel made by Koobl Daroo Co. at a daily dose of 20 mg/kg is prescribed for 3 months and in control group, 0.5-1 mg/kg Propranol tablet made by the same company is prescribed in two divided doses.
Main outcome variables:
After 3 months and then 6 months, the severity, duration, number of headache attacks per month, the rate of headache disability and the side effects of medications are evaluated.