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Effect of short-term coenzyme Q10 supplementation and one session of training on serum total antioxidant capacity, malondiadehyde and Creatine kinase in elite male rock climbers
The purpose of the present study is to investigate Coenzyme Q10 and rock climbing effect on oxidative damages. A total of twenty elite male rock climbers in a randomized and double-blind design will be allocated in two equal groups: supplement (2.5 mg/kg/day Coenzyme Q10) and placebo (2.5 mg/kg/day dextrose) groups. After the supplementation period (14 days), all subjects will participate in an indoor exhaustive climbing protocol for 60 minutes. Blood samples will be obtained before the Q10 supplementation along with before and after the exhaustive exercise protocol. The serum total antioxidant capacity (TAC) and Malondialdehyde (MDA) will be measured by FRAP and spectrophotometer, respectively. The serum IL-6 and C-reactive protein will be determined by ELISA and immunophotometry methods, respectively. The peripheral blood leukocytes counts and CK activity will be determined by automatic analyzer and spectrophotometer, respectively.
IRCTID: IRCT201010114663N2
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