Study aim: To assess the effect of positive thinking counseling and cognitive restructuring versus control group on the perceived stress caused by the repeated failure of in vitro fertilization (IVF) among infertile women Design: This is a randomized clinical trial with control group, in which eligible patients will be randomly assigned through the block randomization to the intervention and control groups Settings and conduct: This study will be performed in the Fatemieh Hospital in Hamadan city on 60 eligible infertile women. The patients will be randomly assigned to the intervention and control groups through the block randomization. This trial will be Blinding is not possible in this study. Participants/Inclusion and exclusion criteria: Inclusion criteria: Age 20 to 45 years Perceived high stress Primary infertility A history of two failed IVFs Normal body mass index Exclusion criteria: Mental disorder History of endometriosis Addiction Intervention groups: Intervention group: Routine treatment plus positive thinking and cognitive restructuring counseling sessions for 45 to 60 minutes twice a week for 4 weeks (including familiarity with types of female infertility, positive and negative emotions, stress and quality of life; positive effect of healthy nutrition, exercise, and meditation on reproductive health; teaching behavioral methods such as talking about stress, calming and postponing the reaction; the effect of positive emotions on the quality of married life and sexual performance of couples) Control group: Just routine treatment Main outcome variables: Primary outcome: Perceived stress