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Study aim: To evaluate the effectiveness of listening to instrumental Western classical music on improving cognitive function and mood, and reducing post‑concussion symptoms in patients with mild traumatic brain injury. Design: A phase II randomized, double‑blind, parallel‑group controlled clinical trial in 100 patients; allocation to music therapy or control groups using variable block randomization. Settings and conduct: After informed consent, patients ≥18 years old with mild traumatic brain injury admitted to Imam Hossein Hospital will be enrolled and randomly assigned to music therapy or control groups using variable block randomization. The intervention group will listen to instrumental classical music for 1 hour daily until 14 days after discharge, while the control group will receive standard care only. Assessments will be performed at admission and at 2 weeks, 1, 3, 6, and 12 months after discharge. Participants/Inclusion and exclusion criteria: Patients ≥18 years old with an initial diagnosis of mild traumatic brain injury admitted to general wards. Inclusion criteria: ability to understand and follow study instructions, access to a music player and headphones, and willingness to participate in follow‑up. Exclusion criteria: prior TBI, major neurological disease, severe psychiatric disorder, significant hearing impairment, active substance or alcohol abuse, or inability to complete questionnaires. Intervention groups: Intervention group: In addition to standard care, patients will listen to instrumental Western classical music with headphones for 1 hour daily from day 2–3 of hospitalization until 14 days after discharge and record it. Control group: Patients will receive standard care only Main outcome variables: The Cambridge Neuropsychological Test Automated Battery (CANTAB)
IRCTID: IRCT20120910010800N17
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