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compare the effect of Nigella Sativa powder in the supplement group and placebo on the Serum Levels of Thyroid Hormones, Beta Transforming Growth Factor, Interlukin 23, Lipid Pattern and markers of oxidative stress in Hashimoto’s Thyroiditis patients
The aim of this randomized, placebo-controlled trial is to investigate the effects of Nigella sativa powder on serum Levels of Thyroid Hormones, Beta Transforming Growth Factor, Interleukin 23, lipid profile and markers of oxidative stress in Hashimoto’s Thyroiditis patients. Forty Hashimoto’s Thyroiditis patients that their disease was confirmed by pathological assessment will be enrolled in this study according inclusion and exclusion criteria. The participants will be assigned into control and treatment groups using permuted-blocks randomization and will be studied in Double-Blind way. Treatment group will receive 2 gram of Nigella sativa powder daily and Placebo Group will receive 2 gram of starch daily along with their lunch and dinner meals for 8 weeks. demographic information, Physical Activity, and 24-hour recall Questionnaire will be completed before and 2 month after the intervention. Blood Samples (7CC) will be taken before and after the intervention and will be kept under -70 Celsius for the relevant tests.Related biochemical measurements will be done by Elisa Kits.
IRCTID: IRCT2014090819082N2
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