Objective: The effect of pelvic floor muscle exercise with mindfulness on sexual function in women with multiple sclerosis. The study population: consist of multiple sclerosis patients who have had recorded accounts in Vice-Chancellor in treatment affairs of Yasuj University of Medical Sciences. Inclusion and exclusion criteria: Inclusion criteria include diagnosis of multiple sclerosis by a physician; having at least literacy and having at least conditions for participate to study. Exclusion criteria included relapses during the intervention. Sample size: 25 patients pelvic floor muscle exercise group (group 1), 25 patients in the group mindfulness (Group 2) and 25 patients in the group pelvic floor muscles exercise with mindfulness(Group 3) and 25 patients in the control group were allocated. In Group 1 pelvic exercise program presented As a group to research units And they will be asked during an 8-week, two times a day to do exercise, so that way every time exercises should be 10 contraction 5 to 10 seconds in a state lying, sitting and standing and subsequent 10 seconds of rest is recommended. In Group 2, during 8 weeks, once a week, every 90 minutes for group runs mindfulness program. In Group 3 during the 8-week Both pelvic floor muscle exercises and mindfulness will be implemented.In group 4, there will be no intervention and only routine treatments will be received. Primary Outcome: sexual function in women with MS