Background and aim: The overall goal of this study is to evaluate the effectiveness of a physical activity prescription on type 2 diabetic patients’ quality of life. Material & methods: consenting eligible type 2 diabetic patients referred to endocrine research clinic of Iran University of Medicine will be enrolled in the study by convenience method. They then will be randomly allocated in two 40 person groups (block randomization) receiving either routine education about life style modification or the physical activity prescription plus the routine education. The WHO quality of life questionnaire will be completed by each participant at the beginning of the study and then 3 months after the enrollment. Patients in the prescription group will receive set tables of physical activity which they will bring to each visit. The physical activity questionnaire IPAQ (long form) will be completed for each participant at first, 1.5 and 3months visits. The results will be analyzed and compared between the 2 groups and if effective the physical activity prescription will be included in the routine type 2 diabetic patients’ care.