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This is a double blind controlled clinical trial in which patient aged between 18-70 years old with mild to moderate UC, in spite of maximum mesalamine treatment, divided in two groups of corchomin+mesalamine and placebo+mesalamine group, which is taken twice a day after breakfast and lunch. The diagnosis of UC was confirmed by endoscopy.
Sinacorchomine is a soft gelatinous capsule containing 40 and 80 milligram of nanomisceles of corchomine (minoo-tehran factory). Placebo is a soft gelatinous capsule without efficient corchomin products. At the beginning of the study all patients will be taught about appropriate diet and lifestyle. Patients will be visited every month for delivery of previous drug packages and handing over new capsules. Also taking pills will be followed every week with phone calls.