Study aim: The objective of this clinical trial study is to evaluate the ability of mini-screw as a micro-perforation device to accelerate canine retraction in orthodontic patients. Additionally, we will investigate the pain and discomfort of the patient during the study. Design: The study is double blind randomized clinical trial with split mouth design. Settings and conduct: Both maxillary canines will be retracted, and movement will be measured every 28 days in three intervals. Pain and discomfort will be monitored with a visual analogue scale. Participants/Inclusion and exclusion criteria: Class II division 1 or Class I bimaxillary dentoalveolar protrusion Mild or no crowding No previous orthodontic treatment No history of systemic disease Good oral hygiene No radiographic evidence of bone loss No history of periodontal therapy and active periodontal disease Probing depth less than 4 mm across the entire dentition No gingivitis or active carious lesion Gingival index and plaque index value less than 1 No smoking Intervention groups: Ten patients with Class II Division 1 or Class I bimaxillary protrusion malocclusion will be selected. Four month after first premolar extraction, just before canine retraction micro-osteoperforation will be created in experimental side of each patient. The control side will not receive micro-osteoperforations. Main outcome variables: rate of canine movement pain and discomfort after micro-osteoperforation