Study aim: Determining and comparing the effect of acupressure and foot reflexology massage on the quality of sleep and fatigue of leukemia patients admitted to Imam Khomeini Hospital Urmia in 1401 Design: A controlled, parallel-group, single-blind, randomized, phase 3 clinical trial on 102 patients. For randomization, cards (a), (b) and (c) were used. Settings and conduct: This study is a single blind clinical trial research with a pre-test-post-test design. It will be implemented in Urmia University of Medical Sciences, Urmia Imam Khomeini Hospital Participants/Inclusion and exclusion criteria: Consent of patients to participate in the study suffering from chronic lymphoid leukemia Age above 18 years and less than 80 years Ability to speak Persian Intervention groups: In the acupressure group, in parallel with these routine cares, acupressure will be performed for each sample using the SP6 point for four weeks and every day (5 minutes) by the researcher. It should be mentioned that the researcher had personally attended all the necessary training related to acupressure and foot massage therapy from the complementary medicine specialist of Urmia University of Medical Sciences (Dr. Nozad; head of the Iranian Complementary Medicine Association) and received the necessary certificate. has done (appendix). In the foot massage therapy group, the intervention will be such that for the patients of this intervention group, after preparing the patient and greasing the soles of the feet with sweet almond oil, which is used for cold and wetness for all temperaments, every day for four consecutive weeks Reflexology is performed for 5 minutes on the treatment points on the soles of both feet. No intervention will be done in the control group and they will only receive routine ward care. Main outcome variables: quality of sleep and fatigue of patients