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Study aim:
evaluate the efficacy (rTMS) as an adjunct therapy in combination with medication and localization in Iranian patients.
Design:
Two arm parallel group randomized trial with blinded
postoperative care and outcome assessment. Random
allocation will be used in this trial based on balance block
randomization and by 4:1 blocks. To do study with
concealment, table of block will be used by one of
researchers, other than interviewer and who assess
patients in follow-up visits, to write number of each
participants on box of additional drugs. Therefore, all of
patients, interviewer and who assess patients in follow-
up visits will be unaware if each number belongs to
which groups.
Settings and conduct:
Patients with a history of OCD who referred to the 22-Bahman Hospital's Psychiatric Clinic were interviewed by a psychiatrist who had DSM5 diagnostic criteria for obsessive-compulsive disorder
Participants/Inclusion and exclusion criteria:
age 18-60 years History of moderate to severe persistent OCD
The subjects did not score above 17 according to the Beck Depression questionaaire
Exclusion criteria
association with other psychiatric illnesses,
history of epilepsy
history of drug abuse
history of neurosurgery complications
having any type of metal implant
Intervention groups:
Group A was treated with(rTMS) for 5 days (5,200 pulses / day) for 3 weeks at the same time as taking the drug While patients in group "B" were only treated with standard medication and sham was used for them so that the device was placed on their scalp without magnetic stimulation
Main outcome variables:
Severity of obsessive-compulsive disorder