Study aim: Comparison of the effect of acupressure and electrical skin stimulation on pain intensity, nausea and vomiting, hypothermia and hemodynamic status after laparoscopic cholecystectomy Design: This study will be performed on 114 patients (male / female) candidates undergoing laparoscopic cholecystectomy who meet the inclusion criteria in the operating room of Al-Zahra Hospital in Isfahan in 2020. And were randomly divided into three groups: 1 control group and 2 intervention groups. Settings and conduct: The researcher and the participant have been blinded. The study in Alzahra Hospital of Isfahan on laparoscopic cholecystectomy patients under general anesthesia was performed in 2020 and includes three groups of acupressure at pc6 point and electrical stimulation of this point with tens device and control group. Participants/Inclusion and exclusion criteria: Entry requirements: The patient's willingness and satisfaction to participate in the intervention، The patient is fully conscious، The target organ should not have an anatomical problem in terms of performing acupressure and Acupressure-Trans Electrical nerve Stimulation (Acu-Tens ) at PC6 point( One of the points in acupuncture in Acupuncture)، All patients underwent general anesthesia with the same medication، Patients are between 30-60 years old Do not have neurological or psychiatric illnesses (according to the patient) or a specific illness Be in ASA I, II category. No entry conditions: History of acute and chronic nausea and vomiting (such as gastrointestinal and ear disorders) ،Drug and alcohol addiction، History of using acupressure Intervention groups: The control group includes participants who are not interfered with. The intervention group with acupressure includes participants who are applied acupressure at the designated pc6 point. Another intervention group includes people who are electrically stimulated at this point on the pc6 using a tens device Main outcome variables: Pain, nausea, vomiting, chills, hemodynamic status, acupressure, electrical stimulation