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Study aim: Examining the effectiveness of amygdala and insula retraining (AIR) program on psychological indicators and sleep patterns in fibromyalgia patients. Design: Clinical trials with control group, parallel groups, single-blind, randomized, phase 3, 50 patients Settings and conduct: This study is a single-blind clinical trial. The statistical population includes patients with fibromyalgia referred to Farabi Hospital in Kermanshah, 50 of whom will be randomly selected and divided into three groups. The first group will receive Amygdala and Insula recovery intervention program, physical activity, and the third group will receive control. All people in all three groups are evaluated by completing the questionnaire at the beginning, 8 weeks later and four weeks after the end of the study in the follow-up test. Participants/Inclusion and exclusion criteria: Both genders, having an FM diagnostic in accordance with the American College of Rheumatology (ACR) 1990 criteria and provided by a rheumatologist working for the Iranian National Health Service, Being able to read and understand Persian Intervention groups: The Amygdala and Insula retraining (AIR) intervention group will include psychotherapy focused on improving skills and coping strategies for stressful situations in 8 weeks and 2 sessions per week. The physical activity group will include aerobic exercises in 8 weeks and 2 sessions per week. The protocol of the passive control group will be to meet each other and gather in 8 weeks and 2 times a week. Main outcome variables: Depression symptoms, Anxiety, Stress, Emotion regulation, Insomnia severity, Sleep quality
IRCTID: IRCT20210119050079N2
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