Study aim: Comparison of effect of interventions on the side effects of chemotherapy in women with breast cancer will be studied. Design: a clinical trial with a control group; with factorial group, randomized on 96 women with breast cancer Settings and conduct: The field of breast cancer study will be conducted in Baqiyatullah and Shahid Chamran Hospitals. Participants will be divided into two groups: test and control Two groups of the test group, one group will be subjected to lavender aroma therapy and the other group will be subjected to acupressure at point p6. The quality of life and depression questionnaire will be filled by the three groups before and four weeks after the intervention. Participants/Inclusion and exclusion criteria: Entry study: suffering from breast cancer for 1-3 years; having mild and moderate depression based on the Beck depression questionnaire, not taking antidepressants, anti-anxiety drugs, psychoactive substances, alcohol, tobacco;Reading and writing literacy; Marriage, lack of mental problems according to the statement of the person or family member; lack of olfactory disorders, eczema and hives or allergies to flowers, plants and respiratory problems; 60-18 years Exit criteria: Avoiding further participation in the study at any stage; reaction to aromatherapy or acupressure; Aggravation of the disease during the study. Intervention groups: Dividing people by random allocation into three groups: aromatherapy, acupressure and control group In aroma therapy group, lavender scent will be used by inhalation for 3 days a week for four weeks. In acupressure group, pressure in the P6 area will be done with both hands three days a week for 4 weeks. For patients in the control group, no intervention is performed Main outcome variables: Quality of life, depression