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Study aim: To evaluate the efficacy and safety of plasma pen assisted minor oral surgery comarared to conventional minor oral surgery for the treatment of reactive exophytic soft tissue lesions Design: Two arm parallel group, non-blinded randomised clinical trial on 30 patients. Randomized computer number generator will be used. Settings and conduct: The subjects will be selected from patients visiting the Oral Medicine Department of Shiraz University of Medical Sciences. After baseline examination,the lesions will be completely excised using a plasma pen or surgical blade according to the standard oral surgical procedures. After retracting the basal part of the lesion superiorly using a clamp, excision will be performed such that the borders were in the intact tissue. It is important to note that the wounds made after the excision with plasma pen will be allowed for secondary healing. In contrast, wounds made with surgical blade will be closed primarily by suture after bleeding is controlled. Thereafter, the patients will be instructed to rinse the mouth with chlorhexidine ۰.۲% once a day for one week. The use of acetaminophen (۵۰۰ mg every ۶ hours) will be considered only if the patient have pain within the first ۲۴ hours after surgery. Participants/Inclusion and exclusion criteria: Inclusion Criteria: 1.subjects aged ۱۸ years or older 2.subjects diagnosed with reactive exophytic oral soft tissue lesions (less than one centimeter) on the buccal mucosa 3.subjects who are willing to participate in this study Exclusion Criteria: 1.Any subject diagnosed clinically with possible neoplastic changes 2.Any subject diagnosed with systemic diseases that could interfere with wound healing Intervention groups: Control Side: Lesion excision using a plasma pen Intervention group:Lesion excision using a surgical blade Main outcome variables: Pain Level; Wound Healing; Complications
IRCTID: IRCT20231213060357N2
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