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Study aim:
Comparison of the effect of propolis mouthwash and 0.02 chlorhexidine on the complications of mandibular impacted third molar surgery.
Design:
Phase 3 clinical trial, with cross-over groups, sample size of 20 people, randomized by throwing dice, double-blind
Settings and conduct:
The current study is a split mouth clinical trial study, which will be conducted in order to investigate the effect of propolis mouthwash intervention on complications caused by mandibular impacted third molar surgery. All participants will be explained about the intervention, its goals, possible side effects and effects, participants, service providers and people who will perform the data analysis will be blinded to the type of grouping and receiving the type of intervention.
Participants/Inclusion and exclusion criteria:
Inclusion criteria:
Above 18 years old
Healthy people (ASA I or II) (healthy people, a person who has a mild systemic disease and the disease is under control and has not caused any restrictions to the patient)
People who need bilateral mandibular impacted third molar surgery (with impact grade one and A based on the Pelland Gregory standard)
Not taking antibiotics for at least 2 weeks
Absence of any inflammation and acute infection in the surgical area
Absence of pregnancy and breastfeeding
Absence of smoking and tobacco addiction
Not allergic to honey
Exclusion criteria:
Lack of cooperation and adherence to protocols
Smoking and tobacco use
Intervention groups:
Consumption of propolis mouthwash and 0.02 chlorhexidine mouthwash as two intervention groups for one week, twice a day after breakfast and before bed for 30 seconds.
Main outcome variables:
Swelling rate; pain level; Mouth opening rate