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Study aim: Comparison of the effect of propolis mouthwash and 0.02 chlorhexidine on the complications of mandibular impacted third molar surgery. Design: Phase 3 clinical trial, with cross-over groups, sample size of 20 people, randomized by throwing dice, double-blind Settings and conduct: The current study is a split mouth clinical trial study, which will be conducted in order to investigate the effect of propolis mouthwash intervention on complications caused by mandibular impacted third molar surgery. All participants will be explained about the intervention, its goals, possible side effects and effects, participants, service providers and people who will perform the data analysis will be blinded to the type of grouping and receiving the type of intervention. Participants/Inclusion and exclusion criteria: Inclusion criteria: Above 18 years old Healthy people (ASA I or II) (healthy people, a person who has a mild systemic disease and the disease is under control and has not caused any restrictions to the patient) People who need bilateral mandibular impacted third molar surgery (with impact grade one and A based on the Pelland Gregory standard) Not taking antibiotics for at least 2 weeks Absence of any inflammation and acute infection in the surgical area Absence of pregnancy and breastfeeding Absence of smoking and tobacco addiction Not allergic to honey Exclusion criteria: Lack of cooperation and adherence to protocols Smoking and tobacco use Intervention groups: Consumption of propolis mouthwash and 0.02 chlorhexidine mouthwash as two intervention groups for one week, twice a day after breakfast and before bed for 30 seconds. Main outcome variables: Swelling rate; pain level; Mouth opening rate
IRCTID: IRCT20240302061143N1
  1. Evaluation of the effect of Iranian Propolis mouthwash on some complications of mandibular impacted third molar surgery
  2. Investigating the effect of post-operative antibiotic administration on the complications of impacted and semi-impacted mandibular third molar surgery - a double-blinded randomized clinical trial
  3. Investigating and comparing the effects of chlorhexidine mouthwash and chlorhexidine-boric acid mouthwash combination on the improvement of complications following mandibular third molar surgery.
  4. Comparison of the effectiveness of pomegranate peel extract mouth rinse & normal saline on complications of third molar surgery in patients having third molars
  5. Comparison of Delayed Infection in Envelope and Three-Corner Flaps in Impact Mandibular Third Molar Surgery, a Prospective Study
  6. The effect of music and diazepam on anxiety and pain control during and after surgery of the impactedmandibular third molar
  7. Comparison of Aloe vera mouthwash and Placebo on postoperative complications in patients with bilateral impacted mandibular third molar teeth
  8. Effect of 0.5% metronidazole rinsing solution on the edema and trismus after surgical removal of impacted mandibular third molars: randomised clinical trial
  9. Comparison of effectiveness of three types of irrigating solutions on the complications after mandibular third molar surgery
  10. Studying the effect of herbal mouthwash (propolis) on the reduction of gingival index, plaque index, and prevalence of dry socket in impacted mandibular wisdom teeth compared to chlorhexidine
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