Study aim: Determining the effect of Betty Newman's systemic model on death anxiety, fear of disease progression, and psychosocial adjustment to the disease in patients with multiple sclerosis. Design: Randomized clinical trial with two control and experimental groups, with parallel groups, on 72 patients with Multiple Sclerosis, randomized using a four-size randomized block design. Settings and conduct: MS Academic Committee affiliated with Shahrekord University of Medical Sciences and MS Association The control group will receive only routine training. In addition to routine care, the intervention group will receive a care program based on the Betty Newman nursing model. The intervention group will receive a program based on the Betty Newman model in 4 sessions, each session lasting 40 minutes, in groups (3 groups of 12 people) using educational videos, whiteboards and podcasts and lectures in the community and clinic environment to reduce the likelihood of encountering stressors or reducing reactions to stressors and strengthening flexible and natural defense lines with a focus on the nursing process. Participants/Inclusion and exclusion criteria: 1. Willingness to participate in the study and complete the informed consent form 2. Age 20 years and older 3. Definite diagnosis of multiple sclerosis in patients based on medical records 4. Being literate enough to read and write and understand the research questionnaire 5. Absence of other incurable diseases 6. EDSS criterion less than 4 Intervention groups: The intervention group will receive an educational intervention based on Betty Newman's systems model in four sessions, while the control group will only receive routine hospital education. Main outcome variables: Death anxiety, Fear of disease progression, and Psychosocial adjustment to illness