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Study aim: The general objective of this study is to assess and compare the effectiveness of transdiagnostic cognitive-behavioral therapy and mindfulness-based therapy in mitigating symptom severity related to attention deficit and hyperactivity/impulsivity. Additionally, we aim to address comorbid issues such as anxiety, depression, and emotional dysregulation among adolescents diagnosed with attention deficit hyperactivity disorder (ADHD). Design: A parallel-group, randomized clinical trial will be conducted, involving 30 patients. Randomization will be achieved using a table of random numbers, and blinding procedures will be implemented. Settings and conduct: Following participant selection and randomization, this study will be conducted at the Imam Khomeini Clinic in Tabriz. Blinding procedures will be implemented for participants, outcome assessors, and the individual responsible for statistical data analysis. Participants/Inclusion and exclusion criteria: Inclusion criteria: 1. Being diagnosed with ADHD disorder 2. Being in the age range of 14 to 17 years 3. Receiving a fixed dose of medicine from at least one month before the start of the study Non-inclusion criteria: 1. being diagnoesd with bipolar mood disorder 2. being diagnosed with psychotic disorders 3. being diagnosed with substance use disorder 4. Having serious suicidal thoughts 5. being diagnosed with conduct disorder Intervention groups: First Intervention Group: Participants in this group will receive transdiagnostic cognitive-behavioral therapy (TCBT) over 20 sessions, each lasting 45 minutes. Second Intervention Group: Participants in this group will undergo mindfulness-based therapy (MBT) for 20 sessions, with each session also lasting 45 minutes. Main outcome variables: symptoms of attention deficit and hyperactivity/impulsivity; severity of anxiety; severity of depression; Severity of emotional dysregulation
IRCTID: IRCT20240823062845N1
  1. The Effectiveness of the Unified Protocol for Transdiagnostic Treatment on Improving Symptoms and Psychological and Neuropsychological Indices in Adults with Attention-Deficit/Hyperactivity Disorder Comorbid with other Emotional Disorders: a Clinical Trial Study
  2. Comparing the Effectiveness of the Unified Protocol with Treatment as Usual for Children with Attention Deficit/Hyperactivity Disorder (ADHD) Comorbid with Emotional Disorders
  3. Comparing the effectiveness of unified transdiagnostic versus cognitive behavioral group therapy on treatment outcomes in adolescents with functional gastrointestinal disorders and determination of the mechanisms of change
  4. Comparative Effectiveness of Cognitive Behavioral Therapy and Mindfulness-Based Cognitive Therapy on Executive Functions, Cognitive Disengagement Syndrome, Stress Management, and Quality of Life in Adults with ADHD
  5. Comparison of transferability of remediation and compensation-based cognitive rehabilitation on cognitive and behavioral performance in adolescents with attention deficit-hyperactivity disorders (ADHD)
  6. Comparison of the Effectiveness of Neurofeedback and Yoga on Enhancing Concentration, Attention, and Reducing Anxiety in Children Aged 6 to 11 with Attention-Deficit/Hyperactivity Disorder (ADHD)
  7. Study of the efficacy and safety of vitamin D add-on standard treatment regimen for children with attention-deficit hyperactivity disorder in 7- to 14 year-Old : A 12 weeks randomized, open-label, parallel group Study
  8. Comparing the Effectiveness of Group Emotion-Focused and Behavioral Interventions for mothers in Children with Attention Deficit/Hyperactivity Disorder
  9. The effect of physical activity with and without cognitive demand on the improvement of executive function and behavioral symptoms in children with ADHD
  10. Effectiveness of virtual reality as an adjunctive intervention in the treatment of Attention-Deficit/Hyperactivity Disorder: a clinical trial design
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