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Study aim: Comparison of the efficacy of schema therapy and mindfulness-based cognitive therapy on symptoms, anxiety sensitivity and sleep quality in patients with irritable bowel syndrome Design: Clinical trial with control group, randomized, on 45 patients. Lottery Settings and conduct: 10 sessions of schema therapy were conducted at the research center for an experimental group of 15 people, and 10 sessions of mindfulness-based cognitive therapy were conducted at the research center for another experimental group of 15 people. Participants/Inclusion and exclusion criteria: Diagnosis of irritable bowel syndrome based on Rome IV criteria with confirmation from a gastroenterologist Lack of history of psychotherapy and lack of use of psychiatric medications Intervention groups: intervention groups with schema therapy and mindfulness based on cognitive therapy and a waiting list control group Main outcome variables: irritable bowel syndrome symptoms, anxiety sensitivity, sleep quality
IRCTID: IRCT20250604066062N1
  1. Comparison of self-efficacy theory and self-compassion therapy on depression, self-care behaviors and quality of life of patients with irritable bowel syndrome
  2. Efficacy of group method cognitive-behavioral stress management on reducing ‎symptoms of patients with irritable bowel syndrome with and without co–‎morbidity of depression and anxiety and increase quality of life
  3. Comparing the Effectiveness of Cognitive- Behavioral Therapy and Emotion- Focused Therapy on Resiliency, Tolerance of Distress and Quality of Life in Patients with Irritable Bowel Syndrome
  4. The impact of short-term psychological training on the ability of mindfulness, anxiety sensitivity, and symptoms of irritable bowel syndrome
  5. Determination of the melatonin effect on gastrointestinal symptoms and quality of life in patients with irritable bowel syndrome with and without sleep disorders
  6. The effect of zinc supplementation separately and in combination with probiotics on inflammatory and oxidative stress indicators, the severity of gastrointestinal symptoms, mood disorders, quality of life and sleep in patients with irritable bowel syndrome: a double-blind randomized controlled clinical trial
  7. Effectiveness of Intensive Short term Dynamic Psychotherapy (ISTDP) on the Difficulty in Emotion Regulation, Defense Mechanisms, Quality of Life and Outcome of Treatment in Patients with Irritable Bowel Syndrome
  8. Examining the effectiveness of Unified Protocol on alleviating psychological distress and digestive symptoms in patients with irritable bowel syndrome
  9. Effect of Cognitive behavioral therapy (CBT) on behavioral responses and anxiety for patients with irritable bowel syndrome (IBS)
  10. Efficacy of traditional Persian remedy of Melissa officinalis, Rosa damascena and Pimpinella anisum on clinical symptoms of patients with irritable bowel syndrome constipation-predominant (IBS-C).
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