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Study aim: To investigate the effect of acupuncture with electrical stimulation (EA) compared with electrical stimulation of the posterior tibial nerve (PTNS) in urinary disorders in patients with multiple sclerosis Design: Phase 3 randomized, parallel-group clinical trial (using a random number table) on 38 patients Settings and conduct: protocol for the first group: 12 sessions Electrical stimulation of the posterior tibial nerve by placing a surface electrode behind the medial malleolus and a needle electrode 5 cm cephalad and 1.5 cm behind the medial malleolus with a stimulation frequency of 20 Hz, a pulse width of 200 milliseconds, a voltage of 9 mV, /protocol for the second group: 12 sessions stimulation at specific points related to urinary incontinence with a frequency of 20 Hz Participants/Inclusion and exclusion criteria: Inclusion: Individuals 18 years of age or older / diagnosed with MS by a neurologist who are stable in terms of disease progression (operationally without change in physical or mental symptoms in the past 4 months) / have an EDSS score of less than 6.5 / have sufficient cognitive capacity to complete the evaluation and treatment protocol Exclusion: Pregnancy, previous gynecological, urological and/or neurosurgery, cesarean section or vaginal delivery in the past 6 months, pelvic organ prolapse greater than stage I / have a urinary tract infection / increase in EDSS score of more than 0.5 from baseline Intervention groups: The first intervention group examined the effect of electroacupuncture/the second intervention group examined the effect of PTNS. Main outcome variables: Age/Gender/Urinary Symptoms/Quality of Life/Intervention/Level of Physical Health/Level of Mental Health
IRCTID: IRCT20260209068810N1
  1. Effect of percutaneous posterior tibial nerve stimulation on treatment of lower urinary tract symptom in women patient multiple sclerosis who referred to Emam Khomeini hospital
  2. Comparative effect of Percutaneous Tibial Nerve Stimulation versus Transcutaneous Posterior Tibial Nerve Stimulation efficacy in the treatment of Overactive Bladder Syndrome
  3. Comparing effect of cutaneous posterior tibial nerve stimulation with medical treatment with Solifenacin in patients with overactive bladder
  4. The comparison between Percutaneous posterior tibial nerve stimulation and Biofeedback-assisted pelvic floor muscle training on quality of life and episode of voiding in women with overactive bladder
  5. Comparison of the Effect of Posterior Tibial Nerve Electrical Stimulation with Conventional Treatments on Improving the Control of Functional Retentive Fecal Incontinence in Children
  6. Efficacy of the percutaneous tibial nerve stimulation in the treatment of OABS (Over Active Bladder Syndrome ) in both technique :unilateral and bilateral nerve stimulating
  7. Effects of Planter Vibrator versus Transcutaneous Electric Nerve Stimulation (TENS) on Balance Dysfunction in Patient with Stroke
  8. Comparison of the effects of medical treatment (Duloxetine andSsolifenacine) and Transcutaneous tibia nerve stimulation in the treatment of post- prostatectomy urinary incontinence
  9. Comprasion of efficacy of Drug therapy(Solifenacin Succinate) and physiotherapy(Stimulation of Posterior Tibialis Nerve) on treatment of overactive Bladder and quality of life in Patients with Multiple Sclerosis
  10. The Efficacy of Electro-acupuncture with Kinesiotape Compared to Biofeedback for Controlling Urinary Symptoms in Patients with Urinary Incontinence
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