History
# Registration date Revision Id
3 2018-11-26, 1397/09/05 70828
2 2018-10-27, 1397/08/05 68234
1 2012-12-31, 1391/10/11 11090
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  • Protocol summary

    A randomized clinical trial, with two intervention groups of 100 pregnant women, between November 2018 to September 2019.
    A randomized clinical trial, with two intervention groups of 150 pregnant women, between November 2018 to September 2019.
    کارآزمایی بالینی تصادفی شده، با دو گروه مداخله از 100 خانم باردار، بین آبان 1397 تا شهریور 1398.
    کارآزمایی بالینی تصادفی شده، با دو گروه مداخله از 150 خانم باردار، بین آبان 1397 تا شهریور 1398.
    At Fatemieh Hospital in Hamadan city, under the same conditions as the rest in a quiet room, left lateral position, and empty bladder, the research units after completion of the consent form, are randomly divided into two groups, in one group administration of 50g/250cc of water and in another group, the abdominal palpation of the mother (Leopold maneuver) is carried out in one or two times and the movements of the fetus are graded ( If there is no movement, zero score, if the mother feels the movements of the fetus, score 1, if the examiner feels the movements of the fetus score 2 and if the examiner sees the movements of the fetus score 3, then score 2 or 3 are selected). Non Stress Test for 20 minutes along with cardiac monitoring, movements and fetal heart rate is recorded.
    At Fatemieh Hospital in Hamadan city, under the same conditions as the rest in a quiet room, left lateral position, and empty bladder, the research units after completion of the consent form, are randomly divided into 3 groups (Three groups of 50 people), in one group administration of 50g/250cc of water and in another group, the abdominal palpation of the mother (Leopold maneuver) is carried out in one or two times and the movements of the fetus are graded ( If there is no movement, zero score, if the mother feels the movements of the fetus, score 1, if the examiner feels the movements of the fetus score 2 and if the examiner sees the movements of the fetus score 3, then score 2 or 3 are selected). Non Stress Test for 20 minutes along with cardiac monitoring, movements and fetal heart rate is recorded. One group is also checked with no intervention as a control group.
    در بیمارستان فاطمیه شهر همدان، در شرايط يكسان مانند انجام آزمايش در اتاق ساكت و وضعیت خوابيده به پهلوي چپ و تخلیه مثانه. واحدهاي پژوهش پس از تمايل و تكميل فرم رضايت نامه، به دو گروه تقسيم مي شوند، در يك گروه تجويز 50 گرم قند خوراكي در 250 سي سي آب صورت مي گيرد و در گروه ديگر لمس شكم مادر در حد مانور لئوپولد يك تا دو بار به فاصله 10 دقيقه انجام مي شود، پس از لمس شكم مادر حركات جنين بدين صورت درجه بندي مي شود ( اگر هيچگونه حركتي وجود نداشته باشد نمره صفر، اگر مادر حركات جنين را احساس نمايد نمره 1، اگر معاينه كننده حركات جنين را احساس نمايد نمره 2 و اگر معاينه كننده حركات جنين را مشاهده كند نمره 3 تعلق مي گيرد سپس در افرادي كه نمره 2 يا3 را كسب مي كنند انتخاب می شوند). تست بدون استرس به مدت 20 دقيقه با همراهي مانيتورينگ قلبي، تعداد حركات و تعداد ضربان قلب جنين ثبت مي گردد.
    در بیمارستان فاطمیه شهر همدان، در شرايط يكسان مانند انجام آزمايش در اتاق ساكت و وضعیت خوابيده به پهلوي چپ و تخلیه مثانه. واحدهاي پژوهش پس از تمايل و تكميل فرم رضايت نامه، به 3 گروه 50 نفره تقسيم مي شوند، در يك گروه تجويز 50 گرم قند خوراكي در 250 سي سي آب صورت مي گيرد و در گروه ديگر لمس شكم مادر در حد مانور لئوپولد يك تا دو بار به فاصله 10 دقيقه انجام مي شود، پس از لمس شكم مادر حركات جنين بدين صورت درجه بندي مي شود ( اگر هيچگونه حركتي وجود نداشته باشد نمره صفر، اگر مادر حركات جنين را احساس نمايد نمره 1، اگر معاينه كننده حركات جنين را احساس نمايد نمره 2 و اگر معاينه كننده حركات جنين را مشاهده كند نمره 3 تعلق مي گيرد سپس در افرادي كه نمره 2 يا3 را كسب مي كنند انتخاب می شوند). تست بدون استرس به مدت 20 دقيقه با همراهي مانيتورينگ قلبي، تعداد حركات و تعداد ضربان قلب جنين ثبت مي گردد. یک گروه نیز به عنوان گروه کنترل بدون هیچگونه مداخله ایی بررسی می شوند.
  • General information

    Not blinded
    Single blinded
    1
    100
    150
    2013-02-28, 1391/12/10
    2018-12-22, 1397/10/01
    2013-12-28, 1392/10/07
    2019-09-23, 1398/07/01
    Single blind, data analyzer will be blind.
    يك سويه كور، آنالیز کننده داده ها کور خواهد شد.
  • Intervention groups

    #1
    empty
    Diagnosis
    empty
    Control group:
    empty
    گروه کنترل:

Protocol summary

Study aim
Comparison of the effects of oral glucose solution or maternal abdominal palpation on non stress test.
Design
A randomized clinical trial, with two intervention groups of 150 pregnant women, between November 2018 to September 2019.
Settings and conduct
At Fatemieh Hospital in Hamadan city, under the same conditions as the rest in a quiet room, left lateral position, and empty bladder, the research units after completion of the consent form, are randomly divided into 3 groups (Three groups of 50 people), in one group administration of 50g/250cc of water and in another group, the abdominal palpation of the mother (Leopold maneuver) is carried out in one or two times and the movements of the fetus are graded ( If there is no movement, zero score, if the mother feels the movements of the fetus, score 1, if the examiner feels the movements of the fetus score 2 and if the examiner sees the movements of the fetus score 3, then score 2 or 3 are selected). Non Stress Test for 20 minutes along with cardiac monitoring, movements and fetal heart rate is recorded. One group is also checked with no intervention as a control group.
Participants/Inclusion and exclusion criteria
- Age 18 to 35 - Gestational age 34 to 41 weeks - Single pregnancy - No history of infertility - regular pregnancy care - Not any illness in pregnancy (diabetes, blood pressure and ...) - normal glucose tolerance test at 28-24 weeks of gestation - No smoking - No infection of Hydramnios, Intrauterine death and ... - No recognize congenital anomalies of the fetus - Not use narcotics, opiates or other drugs by the mother
Intervention groups
The research units were randomly divided into two groups, one group administered 50 grams of oral sugars in 250 cc of water and in the other group, the abdominal palpation of the Leopold maneuvered, one or two times with 10 minutes interval, is done.
Main outcome variables
Fetal movement

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT2012082110635N1
Registration date: 2012-12-31, 1391/10/11
Registration timing: prospective

Last update: 2018-12-15, 1397/09/24
Update count: 2
Registration date
2012-12-31, 1391/10/11
Registrant information
Name
Soodabeh Aghababaei
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 81 3838 0150
Email address
aghababaii@yahoo.com
Recruitment status
Recruitment complete
Funding source
Vice chancellor for Research and Technology Research, Hamadan medical university of Iran.
Expected recruitment start date
2018-12-22, 1397/10/01
Expected recruitment end date
2019-09-23, 1398/07/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Assessment of oral glucose solution & maternal abdominal palpation effect on fetal non stress test.
Public title
Assessment of oral glucose solution & maternal abdominal palpation effect on fetal non stress test.
Purpose
Diagnostic
Inclusion/Exclusion criteria
Inclusion criteria:
Age 18 to 35 years old Gestational age 34 to 41 weeks Single pregnancy Infertility failure Having regular pregnancy care The absence of any illness in pregnancy (diabetes, blood pressure and ...) Having a normal glucose tolerance test at 28-24 weeks of gestation No smoking No Hydramnios and Intrauterine death no recognize congenital anomalies of the fetus to Do not use narcotics, opiates or other drugs by the mother
Exclusion criteria:
abnormal fetal heart rate
Age
To 35 years old
Gender
Female
Phase
2-3
Groups that have been masked
  • Data analyser
Sample size
Target sample size: 150
Randomization (investigator's opinion)
Randomized
Randomization description
Research units are randomly assigned to one of two study groups using random numbers and each group receives one of the relevant interventions.
Blinding (investigator's opinion)
Single blinded
Blinding description
Single blind, data analyzer will be blind.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Hamadan Medical university of Iran
Street address
Hamadan Medical university; Shahid Fahmideh Ave; Hamadan; Iran.
City
Hamadan
Province
Hamadan
Postal code
65178
Approval date
2018-10-13, 1397/07/21
Ethics committee reference number
IR.UMSHA.REC.1397.477

Health conditions studied

1

Description of health condition studied
Non Stress Test
ICD-10 code
O68.9
ICD-10 code description
Labour and delivery complicated by fetal stress, unspecified

Primary outcomes

1

Description
fetal movement
Timepoint
20 minutes after ingestion of 50g of glucose in 250ml of water or Immediately after maternal abdominal palpation.
Method of measurement
fetal non stress test

2

Description
Fetal heart rate
Timepoint
20 minutes after ingestion of 50g of glucose in 250ml of water or Immediately after maternal abdominal palpation.
Method of measurement
fetal non stress test

Secondary outcomes

1

Description
Increase fetal heart rate
Timepoint
At the time of testing
Method of measurement
Fetal heart ratemonitoring

Intervention groups

1

Description
All pregnant women will assess in the same conditions, such as same quiet room and semi recumbent position. Women with non reactive NST randomly assign for oral ingestion of 50g of glucose in 250ml of water, then 20 min monitoring will be done after 30 min of intervention.
Category
Diagnosis

2

Description
All pregnant women will assess in the same conditions, such as same quiet room and semi recumbent position. Women with non reactive NST randomly selected for 1 or 2 times abdominal palpation such as Leopold maneuver with 10 min interval, then 20 min monitoring will be done immediately after intervention.
Category
Diagnosis

3

Description
Control group:
Category
Diagnosis

Recruitment centers

1

Recruitment center
Name of recruitment center
Hamadan Fathemieh Hospital
Full name of responsible person
Aghababaei Soodabeh
Street address
Nursing & Midwifery Faculty; Hamadan Medical university; Shahid Fahmideh Ave; Hamadan; Iran.
City
Hamadan
Province
Hamadan
Postal code
65187
Phone
+98 81 3838 0150
Email
aghababaii@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice Chancellor for Research and Thecnology Research, Hamadan university of Medical Sciences
Full name of responsible person
Dr Said Bashirian
Street address
Vice Chancellor for Research and Thecnology Research; Hamadan Medical university; Shahid Fahmideh Ave; Hamadan; Iran.
City
Hamadan
Province
Hamadan
Postal code
65187
Phone
+98 81 3838 0717
Fax
+98 81 3838 0130
Email
info.research@umsha.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice Chancellor for Research and Thecnology Research, Hamadan university of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Nursing & Midwifery Faculty; Hamadan Medical university of Iran.
Full name of responsible person
Aghababaei Soodabeh
Position
Assistant Professor
Latest degree
Ph.D.
Other areas of specialty/work
بهداشت باروری
Street address
Nursing & Midwifery Faculty; Hamadan Medical university; Shahid Fahmideh Ave; Hamadan; Iran.
City
Hamadan
Province
Hamadan
Postal code
38698-65178
Phone
+98 81 3838 0535
Fax
+98 81 3838 0447
Email
aghababaii@yahoo.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Hamadan Medical university of Iran
Full name of responsible person
Aghababaei Soodabeh
Position
Assistant Professor
Latest degree
Ph.D.
Other areas of specialty/work
Midwifery
Street address
Nursing & Midwifery Faculty; Hamadan Medical university; Shahid Fahmideh Ave; Hamadan; Iran.
City
Hamadan
Province
Hamadan
Postal code
38698-65178
Phone
+98 81 3838 0535
Fax
+98 81 3838 0447
Email
aghababaei@umsha.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Hamadan Medical university of Iran
Full name of responsible person
Soodabeh Aghababaei
Position
Assistant Professor
Latest degree
Ph.D.
Other areas of specialty/work
Midwifery
Street address
Nursing & Midwifery Faculty; Hamadan Medical university; Shahid Fahmideh Ave; Hamadan; Iran.
City
Hamadan
Province
Hamadan
Postal code
38698-65178
Phone
+98 81 3838 0535
Fax
+98 81 3838 0447
Email
aghababaei@umsha.ac.ir
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
Title and more details about the data/document
-
When the data will become available and for how long
-
To whom data/document is available
-
Under which criteria data/document could be used
-
From where data/document is obtainable
-
What processes are involved for a request to access data/document
-
Comments
-
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