Investigation the effect of preoperation oral and infusion riched carbohydrate diet on postoperative nausea ,vomiting and quality of recovery in laparascopic cholecystectomy surgery

Target: Investigation the effect of preoperation oral and infusion riched carbohydrate diet on postoperative nausea, vomiting and quality of recovery in laparascopic cholecystectomy surgery. In a randomized clinical trial, single blind (only patient), non-diabetic candidate patients administered to Rasoul Akram Hospital in 1396 for laparascopic cholecystectomy surgery considered in the study. After informed consent, patients are divided into 3 groups randomly by a non-independent researcher according to the computer number generator. Any group assign to receive a specific diet; Group 1: Infusion of 250 ml dextrose 10%, 2 hours before operation Group 2: 200 ml oral carbohydrate solution (25 gr dextrose), 2 hours before operation Group 3: control group with normal diet and no perception glucose and sugar. Last given meal to all groups is at 8 hours before operation and use of non-carbohydarte oral liquids are prevented 4 hours before surgery. All patients are preperdfor surgery in a same condition. Blood glucose of 3 groups is determined 2 hours before surgery right before study fluid infusion. During all stages of surgery, any patients of any groups will not receive any IV carbohydrate infusion. Anesthetic techniques are equal for every groups. The laparascopic surgery is the choice method for all patients. After surgery Acetaminophen 15 mg/kg, TID is infused for all patients and Plasil ampulla 10 mg altimately TID considered in case of nausea if needed. Any consumption of antiemetic or antianalgesic drugs must be recorded in type, dose and number of using. Blood sugar is evaluated immediately after surgery in recovery room and also in first day after operation at 8:00 AM. It is asked the patient to inform their desire to eat to be recorded. The severity of the pain is achived by Visual Analogue Scale (VAS) in 1, 6 and 24 hours after operation. The score of nausea and vomiting is also checked in 1, 6 and 24 hours after operation by using VAS in the first 24 hours after surgery. Quality Of Recovery questionnire (Includes 5 aspects: Patient support, Comfort, Emotions, Physical independance and Pain) will be given to the patients and according to the taken scores and data of every 3 groups, It wil be analized and compared . The camparison of effect of preoperation carbohydrate therapy on nausea and vomiting and quality of recovery after surgery according to the questionnire and measured indicators will be done.

Vice Chanceller of Research, IRAN University of Medical Sciences