Comparison of the effectiveness of Xyla-p and cold needle cream on pain intensity during venipuncture in children under chemotherapy

Comparison of the effectiveness of Xyla-p and cold needle cream on pain intensity during venipuncture in children under chemotherapy

In cold angiocat injection: Place the angiocatheter in a refrigerator-freezer at -20 ° C for at least one hour in a steel box. After identifying the target vein, the angiocatheter is immediately removed from the freezer and a venipuncture is performed. For injection with Xylapi cream: Apply 2.5 grams of xylophone cream on the skin and apply it on 25-20 cm2 of the skin and cover it with a nylon dressing for at least 45 minutes, then perform a venipuncture with an angiocatheter that is kept in room air. complications such as skin allergies.

Sampling will be done in the chemotherapy ward of Sheikh Mashhad Hospital for children with leukemia aged 2-6 years. Children and statistical analysts do not know how to inject.

Inclusion criteria Age of 6 to 2 years, having complete consciousness, sedative medication and Receive chemotherapy every week At least one month has passed since the onset of the disease. the exclusion criteria to the study: Failure to insert the intravenous line with one time cannula insertion

In the first week, as basic information is collected, the injection is performed routinely, without any cream or angiocatheter with a needle at room temperature. In the following weeks, injections will be performed 3 times in one of the 4 methods (The first group is xylophone and cold angiocatheter, the second group of angiocatheter with cold needle and moisturizing cream, the third group of xylophone cream and angiocatheter with room temperature, the fourth group of moisturizing cream and angiocatheter with needle at room temperature.). Therefore, intervention and data collection in each child is measured in 4 times.

Pain

80 patients are selected as simple access based on inclusion and exclusion criteria and then are randomly assigned to 4 groups using 4 random blocks. Random allocation of the subjects will done by using a block random sampling; A: Xyla-p cream and cold needle Angiocatheter,‎ B: Moisturizing cream and cold needle Angiocatheter‎, C: Xyla-p cream and Angiocatheter in room temperature, D: Moisturizing cream and Angiocatheter in room temperature. Blocks will be ABCD,BCDA,CDBA,CDAB,DACB. The order of blocks will be simple randomized.

This is a double-blind study. The participant (child and parent) is not aware of the injection method. The statistical analyzer will not know the injection method and the data will be provided to him in the form of codes A, B, C and D.