Objective: The effect of probiotic Gaz enriched with inulin on the biochemical parameters including fasting plasma glucose, lipid profiles, inflammatory factors and stress oxidative in patients with type 2 diabetes. Study design: Randomized, cross-over double blind, control with normal Gaz. Inclusion criteria: Patients with diabetes type 2 with FBS ≥ 126 mg/dl and less than 15 years of their disease and in the aged 35 to 65 years were included. Exclusion criteria: Elective subjects with replace treatments including hormone or vitamin supplements, patients with chronic kidney disease, liver, lung and chronic or acute inflammatory disease, heart valve disease, short bowel syndrome and allergies, patients' with low immune system ability (autoimmune) and pregnant or lactating women, were excluded. population and sample size: 80 patients with type 2 diabetes among eligible people in Golabchi clinic in Kashan. Intervention: These patients were divided to two groups: intervention group (receive 20 g probiotic Gaz enriched with inulin) and normal group: (receive 20 g normal Gaz). After an overnight fasting, subjects referred for blood drawn. After this stage, blood samples tested. After 6 weeks of experiment, fasting blood samples were tested again. At the end stage, a 2-week wash-out period was designated. In the this stage, all subjects forbid from taking yoghurt or any other fermented food. Then, groups replace for consume 20 g probiotic Gaz enriched with inulin or 20 g Gaz normal for a 6- weeks. Start and end date of intervention: 14 weeks ( February 27, 2012- June 26, 2012). Baseline outcomes: Serum total cholesterol, LDL-cholesterol, HDL-cholesterol and TG, glucose, insulin, HOMA-IR score, hs-CRP, serum calcium, iron, zinc, Na, K, plasma TAC (total antioxidant capacity) and glutathione.