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Protocol summary
The effect of 12 weeks of continuous moderate training on biomarkers of oxidative stress and DNA damage in women rescued from breast cancer
The effect of 12 weeks continuous moderate training and High intensity interval training on biomarkers of oxidative stress and DNA damage in women rescued from breast cancer
The effect of 12 weeks of continuous moderate training and High intensity interval training on biomarkers of oxidative stress and DNA damage in women rescued from breast cancer
تاثیر 12 هفته تمرین تداومی با شدت متوسط برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
تاثیر 12 هفته تمرین تداومی با شدت متوسط و تمرین تناوبی با شدت بالا برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
تاثیر 12 هفته تمرین تداومی با شدت متوسط و تمرین تناوبی با شدت بالا برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
The present study was an applied and quasi-experimental study that was performed in two intervention groups and one control group
Randomization Method: Simple Randomization, Randomization Unit: Individual, Randomization Tool: Random Number Table
was performed on 30 postmenopausal women
The present study was an applied and quasi-experimental study that was performed in two intervention groups and one control group
Randomization Method: Simple Randomization, Randomization Unit: Individual, Randomization Tool: Random Number Table
was performed on 45 postmenopausal women
The present study was an applied and quasi-experimental study that was performed in two intervention groups and one control group Randomization Method: Simple Randomization, Randomization Unit: Individual, Randomization Tool: Random Number Table was performed on 3045 postmenopausal women
پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی بود که در دو گروه مداخله و یک گروه کنترل انجام شد
روش تصادفی سازی: تصادفی سازی ساده، واحد تصادفی سازی: فردی، ابزار تصادفی سازی: جدول اعداد تصادفی
کور نشده است بر روی 30 زن یائسه انجام شد
پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی بود که در دو گروه مداخله و یک گروه کنترل انجام شد
روش تصادفی سازی: تصادفی سازی ساده، واحد تصادفی سازی: فردی، ابزار تصادفی سازی: جدول اعداد تصادفی
کور نشده است بر روی 45زن یائسه انجام شد
پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی بود که در دو گروه مداخله و یک گروه کنترل انجام شد روش تصادفی سازی: تصادفی سازی ساده، واحد تصادفی سازی: فردی، ابزار تصادفی سازی: جدول اعداد تصادفی کور نشده است بر روی 30 زن45زن یائسه انجام شد
This study examined the effect of 12 weeks of moderate-intensity continuous exercise on stress biomarkers in women rescued from breast cancer.This research is a quasi-experimental method that will be performed in an intervention group and a control group.The statistical population of this study includes postmenopausal women after at least six months of terminaion of their treatment for breast cancer. The moderate-intensity continuous exercise group performed exercise for 12 weeks (36 sessions). Each training session is performed using an ergometer Monark 894E for 20-30 minutes and under the full supervision of the physician.The control group did not perform any exercise intervention.Address: (Nutrition Clinic) No.68, Gulfam Alley, Nelson Mandela Street,Tehran
This research is a quasi-experimental method that will be performed in two intervention group and a control group.The statistical population of this study includes postmenopausal women after at least six months of terminaion of their treatment for breast cancer. Two groups of continuous exercise with moderate intensity and intermittent exercise with high intensity performed exercise for 12 weeks (36 sessions). Each training session is performed using an ergometer Monark 894E for 20-30 minutes and under the full supervision of the physician.The control group did not perform any exercise intervention.Address: (Nutrition Clinic) No.68, Gulfam Alley, Nelson Mandela Street,Tehran
This study examined the effect of 12 weeks of moderate-intensity continuous exercise on stress biomarkers in women rescued from breast cancer.This research is a quasi-experimental method that will be performed in antwo intervention group and a control group.The statistical population of this study includes postmenopausal women after at least six months of terminaion of their treatment for breast cancer. The moderate-intensityTwo groups of continuous exercise groupwith moderate intensity and intermittent exercise with high intensity performed exercise for 12 weeks (36 sessions). Each training session is performed using an ergometer Monark 894E for 20-30 minutes and under the full supervision of the physician.The control group did not perform any exercise intervention.Address: (Nutrition Clinic) No.68, Gulfam Alley, Nelson Mandela Street,Tehran
این مطالعه تاثیر 12 هفته تمرین تداومی با شدت متوسط برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان است. پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی بوده که در یک گروه مداخله و یک گروه کنترل انجام خواهد شد. جامعه آماری این پژوهش شامل زنان یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان می باشد. گروه تمرین تداومی با شدت متوسط مداخله ورزشی مربوط به خود را به مدت 12 هفته (36 جلسه) انجام می دهند. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E ) به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام می شود.آزمودنی های گروه کنترل در طی این مدت پیگیری شدند و هیچ مداخله ورزشی انجام ندادند.محل انجام مطالعه تهران کلینیک تغذیه واقع در خیابان نلسون ماندلا.کوچه گلفام.پ68(ساختمان پزشکان گلفام) خواهد بود.
پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی بوده که در دو گروه مداخله و یک گروه کنترل انجام خواهد شد. جامعه آماری این پژوهش شامل زنان یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان می باشد. دو گروه تمرین تداومی با شدت متوسط وتمرین تناوبی با شدت بالا مداخله ورزشی مربوط به خود را به مدت 12 هفته (36 جلسه) انجام می دهند. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E ) به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام خواهد شد.محل انجام مطالعه تهران کلینیک تغذیه واقع در خیابان نلسون ماندلا.کوچه گلفام.پ68(ساختمان پزشکان گلفام) خواهد بود.
این مطالعه تاثیر 12 هفته تمرین تداومی با شدت متوسط برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان است. پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی بوده که در یکدو گروه مداخله و یک گروه کنترل انجام خواهد شد. جامعه آماری این پژوهش شامل زنان یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان می باشد. دو گروه تمرین تداومی با شدت متوسط وتمرین تناوبی با شدت بالا مداخله ورزشی مربوط به خود را به مدت 12 هفته (36 جلسه) انجام می دهند. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E ) به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام می شود.آزمودنی های گروه کنترل در طی این مدت پیگیری شدند و هیچ مداخله ورزشی انجام ندادند.محلخواهد شد.محل انجام مطالعه تهران کلینیک تغذیه واقع در خیابان نلسون ماندلا.کوچه گلفام.پ68(ساختمان پزشکان گلفام) خواهد بود.
Admission requirements: 1. Definitive diagnosis of the disease and the history of cancer based on the records in the medical record. Placement in stage one, two or three diseases and completion of treatment courses (breast resection surgery, chemotherapy, radiation therapy) for at least the last 6 months. Menopause 4. Body mass index more than 25 kg per square meter 5. Body fat more than 30%. Exclusion criteria: 1. Cardiovascular diseases 2. Diabetes 3. Thyroid diseases 4. smoking
Admission requirements: 1. Definitive diagnosis of the disease and the history of cancer based on the records. Placement in stage one, two or three diseases and completion of treatment courses (breast resection surgery, chemotherapy, radiation therapy) for at least the last 6 months. Menopause 4. Body mass index more than 25 kg per square meter 5. Body fat more than 30%. Exclusion criteria: 1.Cardiovascular diseases 2. Diabetes 3. Thyroid diseases 4.smoking
Admission requirements: 1. Definitive diagnosis of the disease and the history of cancer based on the records in the medical record. Placement in stage one, two or three diseases and completion of treatment courses (breast resection surgery, chemotherapy, radiation therapy) for at least the last 6 months. Menopause 4. Body mass index more than 25 kg per square meter 5. Body fat more than 30%. Exclusion criteria: 1. Cardiovascular1.Cardiovascular diseases 2. Diabetes 3. Thyroid diseases 4. smoking4.smoking
Continuous training group of 15 people and control group of 15 people
Continuous training group of 15 people and interval training group of 15 people and control group of 15 people
Continuous training group of 15 people and interval training group of 15 people and control group of 15 people
گروه 15 نفره تمرین تداومی و گروه 15 نفره کنترل
گروه 15 نفره تمرین تداومی و گروه 15 نفره تمرین تناوبی و گروه 15 نفره کنترل
گروه 15 نفره تمرین تداومی و گروه 15 نفره تمرین تناوبی و گروه 15 نفره کنترل
General information
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3045
2022-05-04, 1401/02/14
2022-08-22, 1401/05/31
2022-0508-0422 00:00:00
2022-06-04, 1401/03/14
2022-09-20, 1401/06/29
2022-0609-0420 00:00:00
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Change the title of the article and Adding interval training to the training protocol
Change the title of the article and Adding interval training to the training protocol
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تغییر عنوان مقاله و اضافه شدن تمرین تناوبی به پروتکل تمرینی
تغییر عنوان مقاله و اضافه شدن تمرین تناوبی به پروتکل تمرینی
The effect of continuous moderate training on oxidative stress and DNA damage in breast cancer survivors
The effect of 12 weeks of continuous training and Interval training on oxidative stress and DNA damage in breast cancer survivors
The effect of 12 weeks of continuous moderatetraining and Interval training on oxidative stress and DNA damage in breast cancer survivors
تاثیر تمرین تداومی با شدت متوسط برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
تاثیر 12 هفته تمرین تداومی و تناوبی برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
تاثیر 12 هفته تمرین تداومی با شدت متوسطو تناوبی برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
The effect of 12 weeks of continuous moderate training on oxidative stress and DNA damage in breast cancer survivors
The effect of 12 weeks of continuous training and Interval training on oxidative stress and DNA damage in breast cancer survivors
The effect of 12 weeks of continuous moderatetraining and Interval training on oxidative stress and DNA damage in breast cancer survivors
تاثیر 12 هفته تمرین تداومی با شدت متوسط برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
تاثیر 12 هفته تمرین تداومی و تناوبی برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
تاثیر 12 هفته تمرین تداومی با شدت متوسطو تناوبی برروی بیومارکرهای استرس اکسایشی و اسیب DNA در زنان نجات یافته از سرطان پستان
Intervention groups
#1
Intervention group: Medium intensity continuous training: During the research, this group will perform three sessions of moderate intensity continuous training for 12 weeks and a week. All aspects of this study are in line with the basic principles of the Helsinki Declaration. The present study is an applied and quasi-experimental method that is performed in an intervention group and a control group. The statistical population of this study includes 30 postmenopausal women after at least six months of termination of their treatment for breast cancer. After the initial assessments, the subjects are randomly divided into two groups of 15 people with continuous training and the control group. The subjects of the training group are subjected to sports intervention for 12 weeks. Each training session is performed using the Ergometer Monark 894E bicycle for 20-30 minutes and under the full supervision of the instructor and physician. At each training session, subjects' heart rate information is monitored by a Finnish-made Polar heart rate monitor and the exercise pressure perception rate (Borg scale RPE scale 6 to 20) is monitored and recorded regularly throughout the time.
Intervention group: Medium intensity continuous training: During the research, this group will perform three sessions of moderate intensity continuous training for 12 weeks and a week. All aspects of this study are in line with the basic principles of the Helsinki Declaration. The present study is an applied and quasi-experimental method that is performed in two interventions group and a control group. The statistical population of this study includes 45 postmenopausal women after at least six months of termination of their treatment for breast cancer. After the initial assessments, the subjects are randomly divided into three groups of 15 people with continuous training and interval training and the control group. The subjects of the continuous training are subjected to sports intervention for 12 weeks. Each training session is performed using the Ergometer Monark 894E bicycle for 20-30 minutes and under the full supervision of the instructor and physician. At each training session, subjects' heart rate information is monitored by a Finnish-made Polar heart rate monitor and the exercise pressure perception rate (Borg scale RPE scale 6 to 20) is monitored and recorded regularly throughout the time.
Intervention group: Medium intensity continuous training: During the research, this group will perform three sessions of moderate intensity continuous training for 12 weeks and a week. All aspects of this study are in line with the basic principles of the Helsinki Declaration. The present study is an applied and quasi-experimental method that is performed in an interventiontwo interventions group and a control group. The statistical population of this study includes 3045 postmenopausal women after at least six months of termination of their treatment for breast cancer. After the initial assessments, the subjects are randomly divided into twothree groups of 15 people with continuous training and interval training and the control group. The subjects of the continuous training group are subjected to sports intervention for 12 weeks. Each training session is performed using the Ergometer Monark 894E bicycle for 20-30 minutes and under the full supervision of the instructor and physician. At each training session, subjects' heart rate information is monitored by a Finnish-made Polar heart rate monitor and the exercise pressure perception rate (Borg scale RPE scale 6 to 20) is monitored and recorded regularly throughout the time.
گروه مداخله: تمرین تداومی با شدت متوسط:در طول تحقیق این گروه به مدت 12 هفته و هفته ای سه جلسه تمرینات تداومی با شدت متوسط را انجام خواهد داد. تمام جنبه های این مطالعه مطابق با اصول اساسی بیانیه هلسینکی می باشد. پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی است که در یک گروه مداخله و یک گروه کنترل انجام می شود. جامعه آماری این پژوهش شامل 30 زن یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان است. پس از ارزیابی های اولیه، آزمودنی ها به شکل تصادفی ساده در دو گروه 15 نفره تمرین تداومی و گروه کنترل دسته بندی می شوند. آزمودنی های گروه تمرینی به مدت 12 هفته تحت مداخله فعالیت ورزشی قرار میگیرند.. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E)به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام می شود. در هر جلسه تمرین اطلاعات ضربان قلب آزمودنی ها به وسیله ضربان سنج پلار ساخت فنلاند و میزان درک فشار تمرین (به وسیله مقیاس بورگ RPE مقیاس6 تا 20 ) در طول کل زمان پایش و به صورت مرتب ثبت می شود
گروه مداخله: تمرین تداومی با شدت متوسط:در طول تحقیق این گروه به مدت 12 هفته و هفته ای سه جلسه تمرینات تداومی با شدت متوسط را انجام خواهد داد. تمام جنبه های این مطالعه مطابق با اصول اساسی بیانیه هلسینکی می باشد. پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی است که در دو گروه مداخله و یک گروه کنترل انجام می شود. جامعه آماری این پژوهش شامل 45 زن یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان است. پس از ارزیابی های اولیه، آزمودنی ها به شکل تصادفی ساده در سه گروه 15 نفره تمرین تداومی و گروه تمرین تناوبی و گروه کنترل دسته بندی می شوند. آزمودنی های گروه تمرین تداومی به مدت 12 هفته تحت مداخله فعالیت ورزشی قرار میگیرند.. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E)به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام می شود. در هر جلسه تمرین اطلاعات ضربان قلب آزمودنی ها به وسیله ضربان سنج پلار ساخت فنلاند و میزان درک فشار تمرین (به وسیله مقیاس بورگ RPE مقیاس6 تا 20 ) در طول کل زمان پایش و به صورت مرتب ثبت می شود
گروه مداخله: تمرین تداومی با شدت متوسط:در طول تحقیق این گروه به مدت 12 هفته و هفته ای سه جلسه تمرینات تداومی با شدت متوسط را انجام خواهد داد. تمام جنبه های این مطالعه مطابق با اصول اساسی بیانیه هلسینکی می باشد. پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی است که در یکدو گروه مداخله و یک گروه کنترل انجام می شود. جامعه آماری این پژوهش شامل 3045 زن یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان است. پس از ارزیابی های اولیه، آزمودنی ها به شکل تصادفی ساده در دوسه گروه 15 نفره تمرین تداومی و گروه تمرین تناوبی و گروه کنترل دسته بندی می شوند. آزمودنی های گروه تمرینیتمرین تداومی به مدت 12 هفته تحت مداخله فعالیت ورزشی قرار میگیرند.. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E)به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام می شود. در هر جلسه تمرین اطلاعات ضربان قلب آزمودنی ها به وسیله ضربان سنج پلار ساخت فنلاند و میزان درک فشار تمرین (به وسیله مقیاس بورگ RPE مقیاس6 تا 20 ) در طول کل زمان پایش و به صورت مرتب ثبت می شود
#2
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Rehabilitation
rehabilitaion
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Intervention group: High intensity interval training:During the research, this group will perform three sessions of high-intensity interval training for 12 weeks.All aspects of this study are in accordance with the basic principles of the Declaration of Helsinki. The current research is applied and semi-experimental in two intervention groups and one control group. The statistical population of this research includes 45 menopausal women after at least six months of breast cancer treatment. After the initial evaluations, the subjects are randomly divided into three groups of 15 people: continuous exercise, intermittent exercise group, and control group.Each exercise session is done using an ergometer Monark 894E bicycle for 20-30 minutes under the full supervision of a trainer and doctor. In each training session, the subject's heart rate information is recorded regularly by means of Polar heart rate monitor made in Finland and the level of perception of training pressure (by Borg RPE scale 6 to 20) during the entire monitoring time. The main training in this group is in At first (the first week), there were four training stages (30 seconds of pedaling and 2 active rests) in a row. The number of steps increases every week until it reaches 7 steps in the fourth week (one step was added every week until the fourth week), from the fourth week to the 12th week, the number of steps is maintained at the same number (7 steps).
Intervention group: High intensity interval training:During the research, this group will perform three sessions of high-intensity interval training for 12 weeks.All aspects of this study are in accordance with the basic principles of the Declaration of Helsinki. The current research is applied and semi-experimental in two intervention groups and one control group. The statistical population of this research includes 45 menopausal women after at least six months of breast cancer treatment. After the initial evaluations, the subjects are randomly divided into three groups of 15 people: continuous exercise, intermittent exercise group, and control group.Each exercise session is done using an ergometer Monark 894E bicycle for 20-30 minutes under the full supervision of a trainer and doctor. In each training session, the subject's heart rate information is recorded regularly by means of Polar heart rate monitor made in Finland and the level of perception of training pressure (by Borg RPE scale 6 to 20) during the entire monitoring time. The main training in this group is in At first (the first week), there were four training stages (30 seconds of pedaling and 2 active rests) in a row. The number of steps increases every week until it reaches 7 steps in the fourth week (one step was added every week until the fourth week), from the fourth week to the 12th week, the number of steps is maintained at the same number (7 steps).
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گروه مداخله: تمرین تناوبی با شدت بالا:در طول تحقیق این گروه به مدت 12 هفته و هفته ای سه جلسه تمرینات تناوبی با شدت بالا را انجام خواهد داد.پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی است که در دو گروه مداخله و یک گروه کنترل انجام می شود. جامعه آماری این پژوهش شامل 45 زن یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان است. پس از ارزیابی های اولیه، آزمودنی ها به شکل تصادفی ساده در سه گروه 15 نفره تمرین تداومی و گروه تمرین تناوبی و گروه کنترل دسته بندی می شوند. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E)به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام می شود. در هر جلسه تمرین اطلاعات ضربان قلب آزمودنی ها به وسیله ضربان سنج پلار ساخت فنلاند و میزان درک فشار تمرین (به وسیله مقیاس بورگ RPE مقیاس6 تا 20 ) در طول کل زمان پایش و به صورت مرتب ثبت می شود.تمرین اصلی در این گروه در ابتدا (هفته اول) ،چهار مرحله تمرین (30 ثانیه پدال زدن و 2 استراحت فعال) پشت سر هم بود. تعداد مراحل هر هفته افزایش می یابد تا زمانی که در هفته چهارم به 7 مرحله خواهد رسید ( هر هفته یک مرحله اضافه می شد تا هفته چهارم) از هفته چهارم تا هفته 12 تعداد مراحل در همین تعداد (7 مرحله ) حفظمی شود.
گروه مداخله: تمرین تناوبی با شدت بالا:در طول تحقیق این گروه به مدت 12 هفته و هفته ای سه جلسه تمرینات تناوبی با شدت بالا را انجام خواهد داد.پژوهش حاضر از نوع کاربردی و به روش نیمه تجربی است که در دو گروه مداخله و یک گروه کنترل انجام می شود. جامعه آماری این پژوهش شامل 45 زن یائسه بعد از حداقل شش ماه خاتمه ی درمان ان ها از سرطان پستان است. پس از ارزیابی های اولیه، آزمودنی ها به شکل تصادفی ساده در سه گروه 15 نفره تمرین تداومی و گروه تمرین تناوبی و گروه کنترل دسته بندی می شوند. هر جلسه تمرینی با استفاده از دوچرخه کارسنج (Ergometer Monark 894E)به مدت 20-30 دقیقه و تحت نظارت کامل مربی و پزشک انجام می شود. در هر جلسه تمرین اطلاعات ضربان قلب آزمودنی ها به وسیله ضربان سنج پلار ساخت فنلاند و میزان درک فشار تمرین (به وسیله مقیاس بورگ RPE مقیاس6 تا 20 ) در طول کل زمان پایش و به صورت مرتب ثبت می شود.تمرین اصلی در این گروه در ابتدا (هفته اول) ،چهار مرحله تمرین (30 ثانیه پدال زدن و 2 استراحت فعال) پشت سر هم بود. تعداد مراحل هر هفته افزایش می یابد تا زمانی که در هفته چهارم به 7 مرحله خواهد رسید ( هر هفته یک مرحله اضافه می شد تا هفته چهارم) از هفته چهارم تا هفته 12 تعداد مراحل در همین تعداد (7 مرحله ) حفظمی شود.
Recruitment centers
#1
Name of recruitment center - English: clinic of nutrition
Name of recruitment center - Persian: مطب تغذیه
Full name of responsible person - English: sahabeh mahdian
Full name of responsible person - Persian: سحابه مهدیان
Street address - English: Raden. Jordan St., Gulfam Alley, No. 68 (Doctors Building) Gulfam, Unit 7
Street address - Persian: خیابان جردن.کوچه گلفام.پلاک 68 (ساختمان پزشکان )گلفام.واحد 7
City - English: tehran
City - Persian: تهران
Province: Tehran
Country: Iran (Islamic Republic of)
Postal code: 1915673499
Phone: +98 21 2621 6051
Fax:
Email: sahabeh_mahdiann@yahoo.com
Web page address:
Name of recruitment center - English: clinic of nutrition
Name of recruitment center - Persian: مطب تغذیه
Full name of responsible person - English: sahabeh mahdian
Full name of responsible person - Persian: سحابه مهدیان
Street address - English: Unit 7 No, 68(Doctors Building), Gulfam Alley, Jordan St, Tehran, iran
Street address - Persian: خیابان جردن.کوچه گلفام.پلاک 68 (ساختمان پزشکان )گلفام.واحد 7
City - English: tehran
City - Persian: تهران
Province: Tehran
Country: Iran (Islamic Republic of)
Postal code: 1915673499
Phone: +98 21 2621 6051
Fax:
Email: sahabeh_mahdiann@yahoo.com
Web page address:
Name of recruitment center - English: clinic of nutrition Name of recruitment center - Persian: مطب تغذیه Full name of responsible person - English: sahabeh mahdian Full name of responsible person - Persian: سحابه مهدیان Street address - English: Raden. Jordan St.Unit 7 No, 68(Doctors Building), Gulfam Alley, No. 68 (Doctors Building) GulfamJordan St, Unit 7Tehran, iran Street address - Persian: خیابان جردن.کوچه گلفام.پلاک 68 (ساختمان پزشکان )گلفام.واحد 7 City - English: tehran City - Persian: تهران Province: Tehran Country: Iran (Islamic Republic of) Postal code: 1915673499 Phone: +98 21 2621 6051 Fax: Email: sahabeh_mahdiann@yahoo.com Web page address:
Sponsors / Funding sources
#1
contact.organization_id:
Name of organization / entity - English: by myself
Name of organization / entity - Persian: خصوصی
Full name of responsible person - English: sahabeh mahdian
Full name of responsible person - Persian: سحابه مهدیان
Street address - English: Unit 7, No.11, Baharan St., Shiraz-South St, Mollasadra St, Vanak Sq, Tehran
Street address - Persian: ملاصدرا.شیراز جنوبی.کوچه اهاران/پلاک11.واحد7
City - English: tehran
City - Persian: تهران
Province: Tehran
Country: Iran (Islamic Republic of)
Postal code: 1435814118
Phone: +98 21 8860 9716
Fax:
Email: sahabeh_mahdiann@yahoo.com
Web page address:
contact.organization_id:
Name of organization / entity - English: Private
Name of organization / entity - Persian: خصوصی
Full name of responsible person - English: Sahabeh mahdian
Full name of responsible person - Persian: سحابه مهدیان
Street address - English: Unit 7, No11, Baharan St, Shiraz South St, Mollasadra St, Vanak Sq, Tehran
Street address - Persian: ملاصدرا، شیراز جنوبی، کوچه بهاران پلاک11، واحد7
City - English: Tehran
City - Persian: تهران
Province: Tehran
Country: Iran (Islamic Republic of)
Postal code: 1435814118
Phone: +98 21 8860 9716
Fax:
Email: sahabeh_mahdiann@yahoo.com
Web page address:
contact.organization_id: Name of organization / entity - English: by myselfPrivate Name of organization / entity - Persian: خصوصی Full name of responsible person - English: sahabehSahabeh mahdian Full name of responsible person - Persian: سحابه مهدیان Street address - English: Unit 7, No.11No11, Baharan St., Shiraz-South St, Mollasadra St, Vanak Sq, Tehran Street address - Persian: ملاصدرا.شیراز جنوبی.کوچه اهاران/پلاک11.واحد7ملاصدرا، شیراز جنوبی، کوچه بهاران پلاک11، واحد7 City - English: tehranTehran City - Persian: تهران Province: Tehran Country: Iran (Islamic Republic of) Postal code: 1435814118 Phone: +98 21 8860 9716 Fax: Email: sahabeh_mahdiann@yahoo.com Web page address:
Protocol summary
Study aim
The effect of 12 weeks continuous moderate training and High intensity interval training on biomarkers of oxidative stress and DNA damage in women rescued from breast cancer
Design
The present study was an applied and quasi-experimental study that was performed in two intervention groups and one control group
Randomization Method: Simple Randomization, Randomization Unit: Individual, Randomization Tool: Random Number Table
was performed on 45 postmenopausal women
Settings and conduct
This research is a quasi-experimental method that will be performed in two intervention group and a control group.The statistical population of this study includes postmenopausal women after at least six months of terminaion of their treatment for breast cancer. Two groups of continuous exercise with moderate intensity and intermittent exercise with high intensity performed exercise for 12 weeks (36 sessions). Each training session is performed using an ergometer Monark 894E for 20-30 minutes and under the full supervision of the physician.The control group did not perform any exercise intervention.Address: (Nutrition Clinic) No.68, Gulfam Alley, Nelson Mandela Street,Tehran
Participants/Inclusion and exclusion criteria
Admission requirements: 1. Definitive diagnosis of the disease and the history of cancer based on the records. Placement in stage one, two or three diseases and completion of treatment courses (breast resection surgery, chemotherapy, radiation therapy) for at least the last 6 months. Menopause 4. Body mass index more than 25 kg per square meter 5. Body fat more than 30%. Exclusion criteria: 1.Cardiovascular diseases 2. Diabetes 3. Thyroid diseases 4.smoking
Intervention groups
Continuous training group of 15 people and interval training group of 15 people and control group of 15 people
Main outcome variables
oxidative stress biomarkers:GPX,SOD,TAC,8-OHdG
General information
Reason for update
Change the title of the article and Adding interval training to the training protocol
Acronym
IRCT registration information
IRCT registration number:IRCT20220418054577N1
Registration date:2022-05-14, 1401/02/24
Registration timing:prospective
Last update:2022-08-17, 1401/05/26
Update count:1
Registration date
2022-05-14, 1401/02/24
Registrant information
Name
Sahabeh Mahdian
Name of organization / entity
University of tehran(physical education and sport)
Country
Iran (Islamic Republic of)
Phone
+98 21 8860 9716
Email address
sahabeh_mahdiann@yahoo.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-08-22, 1401/05/31
Expected recruitment end date
2022-09-20, 1401/06/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of 12 weeks of continuous training and Interval training on oxidative stress and DNA damage in breast cancer survivors
Public title
The effect of 12 weeks of continuous training and Interval training on oxidative stress and DNA damage in breast cancer survivors
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
at least 6 months of complete discontinuation of breast cancer treatment
permission of the physician to participating in the research
women should be on the same levele in terms of health،life ، nutrition ،duration of illness
body mass index shoul be above 25kg/m2.weight of body fat more than 30%
ability to exercise with the approval of an oncologist and cardiologist
menopause
Randomization Method: Simple Randomization, Randomization Unit: Individual, Randomization Tool: Random Number Table
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics Committee of the Institute of Physical Education and Sports Sciences
Street address
No 3, Fifth Alley, Mir Emad St, Ostad Motahhari St, Tehran
City
tehran
Province
Tehran
Postal code
1587958711
Approval date
2021-12-19, 1400/09/28
Ethics committee reference number
IR.UT.SPORT.REC.1400.036
Health conditions studied
1
Description of health condition studied
breast cancer
ICD-10 code
C50
ICD-10 code description
Malignant neoplasm of breast
Primary outcomes
1
Description
Serum SOD levels
Timepoint
48 hours before and after the desired interventions
Method of measurement
Blood sampling using ELISA method
2
Description
Serum GPX levels
Timepoint
48 hours before and after the desired interventions
Method of measurement
Blood sampling using ELISA method
3
Description
Serum TAC levels
Timepoint
48 hours before and after the desired interventions
Method of measurement
Blood sampling using ELISA method
4
Description
Serum MDA levels
Timepoint
48 hours before and after the desired interventions
Method of measurement
Blood sampling using ELISA method
5
Description
Serum 8-OHdg levels
Timepoint
48 hours before and after the desired interventions
Method of measurement
Blood sampling using ELISA method
Secondary outcomes
empty
Intervention groups
1
Description
Intervention group: Medium intensity continuous training: During the research, this group will perform three sessions of moderate intensity continuous training for 12 weeks and a week. All aspects of this study are in line with the basic principles of the Helsinki Declaration. The present study is an applied and quasi-experimental method that is performed in two interventions group and a control group. The statistical population of this study includes 45 postmenopausal women after at least six months of termination of their treatment for breast cancer. After the initial assessments, the subjects are randomly divided into three groups of 15 people with continuous training and interval training and the control group. The subjects of the continuous training are subjected to sports intervention for 12 weeks. Each training session is performed using the Ergometer Monark 894E bicycle for 20-30 minutes and under the full supervision of the instructor and physician. At each training session, subjects' heart rate information is monitored by a Finnish-made Polar heart rate monitor and the exercise pressure perception rate (Borg scale RPE scale 6 to 20) is monitored and recorded regularly throughout the time.
Category
Rehabilitation
2
Description
Control group:The control group consists of 15 postmenopausal women who are followed during this period and do not do any sports intervention and only continue their daily activities and routine medical care.
Category
Lifestyle
3
Description
Intervention group: High intensity interval training:During the research, this group will perform three sessions of high-intensity interval training for 12 weeks.All aspects of this study are in accordance with the basic principles of the Declaration of Helsinki. The current research is applied and semi-experimental in two intervention groups and one control group. The statistical population of this research includes 45 menopausal women after at least six months of breast cancer treatment. After the initial evaluations, the subjects are randomly divided into three groups of 15 people: continuous exercise, intermittent exercise group, and control group.Each exercise session is done using an ergometer Monark 894E bicycle for 20-30 minutes under the full supervision of a trainer and doctor. In each training session, the subject's heart rate information is recorded regularly by means of Polar heart rate monitor made in Finland and the level of perception of training pressure (by Borg RPE scale 6 to 20) during the entire monitoring time. The main training in this group is in At first (the first week), there were four training stages (30 seconds of pedaling and 2 active rests) in a row. The number of steps increases every week until it reaches 7 steps in the fourth week (one step was added every week until the fourth week), from the fourth week to the 12th week, the number of steps is maintained at the same number (7 steps).
Category
Rehabilitation
Recruitment centers
1
Recruitment center
Name of recruitment center
clinic of nutrition
Full name of responsible person
sahabeh mahdian
Street address
Unit 7 No, 68(Doctors Building), Gulfam Alley, Jordan St, Tehran, iran
City
tehran
Province
Tehran
Postal code
1915673499
Phone
+98 21 2621 6051
Email
sahabeh_mahdiann@yahoo.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Private
Full name of responsible person
Sahabeh mahdian
Street address
Unit 7, No11, Baharan St, Shiraz South St, Mollasadra St, Vanak Sq, Tehran
City
Tehran
Province
Tehran
Postal code
1435814118
Phone
+98 21 8860 9716
Email
sahabeh_mahdiann@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Private
Proportion provided by this source
100
Public or private sector
Private
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Persons
Person responsible for general inquiries
Contact
Name of organization / entity
Faculty of Physical Education and Sport Sciences - University of Tehran
Full name of responsible person
parisa pournemati
Position
lecture university
Latest degree
Ph.D.
Other areas of specialty/work
Physiology
Street address
Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, North Kargar St., Iran
City
Tehran
Province
Tehran
Postal code
1417614418
Phone
+98 21 8835 1730
Email
p.pournemati@ut.ac.ir
Person responsible for scientific inquiries
Contact
Name of organization / entity
Faculty of Physical Education and Sport Sciences, University of Tehran
Full name of responsible person
Parisa pournemati
Position
lecture university
Latest degree
Ph.D.
Other areas of specialty/work
Physiology
Street address
Faculty of Physical Education and Sport Sciences, University of Tehran, Iran, Tehran, North Kargar St.tehran. iran
City
Tehran
Province
Tehran
Postal code
1417614418
Phone
1417614418
Email
p.pournemati@ut.ac.ir
Person responsible for updating data
Contact
Name of organization / entity
Faculty of Physical Education and Sport Sciences - University of Tehran
Full name of responsible person
Sahabeh Mahdian
Position
Phd student
Latest degree
Master
Other areas of specialty/work
Physiology
Street address
Faculty of Physical Education and Sport Sciences, University of Tehran, Iran, Tehran, North Kargar St.
City
Tehran
Province
Tehran
Postal code
1417614418
Phone
+98 21 8835 1730
Email
sahabeh_mahdiann@yahoo.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
Not applicable
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Not applicable
Data Dictionary
Not applicable
Title and more details about the data/document
Patients' personal information is confidential. But access to research methods and information obtained from research is not an obstacle
When the data will become available and for how long
Access period starts 6 months after the results are published "
To whom data/document is available
All students and enthusiasts
Under which criteria data/document could be used
To use the data to conduct research in this area
From where data/document is obtainable
Authors of this article: sahabeh_mahdiann@yahoo.com
What processes are involved for a request to access data/document
By sending an email to the author will cooperate with the applicant at the earliest opportunity