Comparing the impact of fentanyl- music therapy, fentanyl- midazolam and ketorolac-midazolam on pain and anxiety of patient undergoing Extracorporeal Shock Wave Lithotripsy

Objectives: determine the effect of fentanyl - midazolam on pain and anxiety of patients treated with ESWL; determine the effect of keterolac- midazolam on pain and anxiety of patients treated with ESWL; determine the effect of Fentanyl - music therapy on pain and anxiety of patients treated with ESWL; compare the effects of Fentanyl - music therapy, keterolac- midazolam and fentanyl - midazolam on pain and anxiety in patients treated with ESWL Design: All patients with urinary stones between 18 and 60 years old referred for ESWL were enrolled to study. Randomization based on ABC blocks and sample size determine with pilot study (10 patients in each group) and patients were placed in groups A: Fentanyl music therapy, B: Keterolac- midazolam, C: Fentanyl- Midazolam. In all three groups, prior to ESWL, anxiety measured by visual analog scale and hemodynamic parameters will be recorded. In Group A: 1μg / kg intravenous fentanyl will be injected and starts the music player with headphones. Group B: ketorolac 30 mg and midazolam 1mg; in Group C: Fentanyl μg / kg and Midazolam 1 mg will be injected and headphones off placed on the patient's head. In all cases, the pain will be measured by numerical rating scale every 10 minutes and after the lithotripsy procedure. Hemodynamic parameters will be recorded initially and then every 10 minutes and at the end of the procedure and anxiety will be recorded at the end of lithotripsy. If the patient was restless during lithotripsy any time or pain score was above 7, with the approval of anesthesiologist dose will be repeated and patient is excluded.

North Khorasan University of Medical Sciences