Comparison of outcomes and complications between anterior repair and resection-anastomosis of small intestine for closure of loop ileostomy performed in patients underwent rectal cancer resetion surgery

Loop ileostomy is a major surgical procedure suggested to control the complications of colorectal anastomosis, especially disruption and anastomosis leakage in patients undergoing resection of the distal rectum cancers. This trial is done to compare two methods of anterior repair and resection and anastomosis of the small intestine for ileostomy closure. For a better and more accurate comparison, we decided to perform the clinical trial in two randomized groups of 20 patients to answer the research questions. Goals: To compare complications after surgery in two groups of anterior repair and resection and anastomosis. These complications include early complications such as anastomosis leakage, infection, bleeding, in addition to late complications such as anastomosis stricture and obstruction. Method and participants: This study is a randomized clinical trial in two groups of 20 patients who underwent LAR surgery for rectal cancer and protective loop ileostomy. Intervention: Patients in two groups were randomly assigned. The first group underwent intestinal resection in the distal and proximal part of ileostomy and then an hand-sewn anastomosis was done. In the second group the anterior defect within the ileostomy was repaired. Main outcomes : first day of defecation / first day of flatus / first day of oral feeding / post operation early complications / post operation late complications

Tehran University of Medical Sciences