Study aim: Comparison of the effectiveness of MBSR and CBT on anxiety, stress, depression, chronic fatigue, executive performance, quality of life and sleep, and decreased disease activity in patients with rheumatoid arthritis Design: This is a randomized study with three groups of MBSR and CBT and the control group. Subsequently, 75 patients with arthritis who have the criteria for entering the thesis will be selected on a sample-based basis. The sampling is based on the goal and Participants were randomly assigned to participate in the intervention and control groups, and all three groups were grouped according to known factors. Subsequently, individuals in the 25-person control, MBSR treatment, and CBT treatment will be replaced. LP Settings and conduct: The place of doing the research in Kashan Shahid Beheshti Hospital was carried out and the patients were referred to the hospital for first sampling and 75 patients were randomly assigned into three groups (two treatment groups, one control group). This research is a blind clinical trial. Members of each group come to treatment for different days and hours, and the members of the three groups do not meet each other. Participants/Inclusion and exclusion criteria: A definitive diagnosis of rheumatoid arthritis Intervention groups: MBSR 8-session treatment once a week CBT 10-session treatment once a week Control group: A group whose members receive the same drugs as the rest of the participants. Main outcome variables: Stress-Depression-Anxiety-Chronic fatigue symptom-Sleep quality-Quality of life-Executive performance-disease activity