Study aim: Comparison of the effect of acupressure of Niguwan (pc6) and Sanyingjao (sp6) points on the severity of post-cesarean section pain in primiparous women. Design: A controlled, parallel-group, single-blind, randomized, phase 1 clinical trial on 108 patients. R software was used for randomization. Settings and conduct: The present study was conducted in Shahid Rahimi Hospital, Khorramabad. The aim of the study is to investigate the effectiveness of acupressure in reducing post-cesarean section pain. Participants will be randomly assigned to three intervention groups (PC6 and SP6 points) and control (sham acupressure) in a block-wise manner. The intervention will be performed twice postoperatively, and pain intensity will be measured at five time points using the VAS scale. All participants will receive routine hospital analgesics. Blinding of participants will be accomplished through the use of sham acupressure and concealed allocation with sealed envelopes. The person recording pain intensity will also be blinded to the type of intervention. Participants/Inclusion and exclusion criteria: Primiparous women with their first cesarean delivery by a designated gynecologist at Shahid Rahimi Hospital in Khorramabad, aged between 18 and 45 years, and singletons without any diseases or problems. Intervention groups: After selecting eligible individuals, their allocation to three intervention groups (acupressure at the PC6 point, acupressure at the SP6 point) and the control group (apparent acupressure without real pressure) will be performed using a block randomization method with a block size of six. Main outcome variables: Reducing pain in women after cesarean section, reducing painkiller use