This study is a randomized clinical trial . The aim of this study is comparison between FSH (follice - stimulating hormone) administration with HCG(human chorionic gonadotropin) at the time of trigger and HCG alone in IVF cycles outcomes. Inclusion criteria : infertile women who candidate for IVF cycles.
Exclusion criteria : women with history of endocrine disorders; serum estradiol>4500 pg/ml in day of trigger;intrauterine abnormality( uterine polyp; uterine myoma).110 infertile women who are candidated for IVF(Invitro fertilization) cycles . They divide in 2 proups : Both of two groups receive antagonist protocol.serum estrogen is checked in day of trigger and patient with estradiol >4500 exclude of study. In case group ,patient receive 450 u FSH(cinnal f) with HCG at the time of trigger.36 hours later in both group,oocyte retrieval is done . Main outcomes: pregnancy test (serum BHCG) is done 2 weeks after ET(chemical pregnancy) . Fetal heart beat is checked 2-3 weeks after positive BHCG test(clinical pregnancy).
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2017082724512N5
Registration date:2017-09-22, 1396/06/31
Registration timing:registered_while_recruiting
Last update:
Update count:2
Registration date
2017-09-22, 1396/06/31
Registrant information
Name
Abbas Aflatoonian
Name of organization / entity
Yazd research and clinical center for infertility
Country
Iran (Islamic Republic of)
Phone
+98 358247085
Email address
abbas-aflatoonian@ssu.ac.ir
Recruitment status
Recruitment complete
Funding source
Yazd Reproductive Sciences Institute ,Shahid Sadoughi University of Medical Sciences.
Expected recruitment start date
2017-09-21, 1396/06/30
Expected recruitment end date
2018-01-20, 1396/10/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison between FSH administration with HCG at the time of trigger and HCG alone in IVF cycles outcomes.
Public title
Comparison between FSH administration with HCG at the time of trigger and HCG alone in IVF cycles outcomes.
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria : Infertile women who candidate for IVF cycles.
Exclusion criteria : women with history of endocrine disorders; serum estradiol>4500pg/ml in day of trigger;intrauterine abnormality( uterine polyp; uterine myoma)
Age
From 20 years old to 40 years old
Gender
Female
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size:
110
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics Committee of Yazd Reproductive Sciences Institute Shahid Sadoughi University