History
# Registration date Revision Id
3 2023-09-27, 1402/07/05 284666
2 2023-03-29, 1402/01/09 260076
1 2022-09-04, 1401/06/13 238930
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  • General information

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    1. Modification of the Code of Ethics Committee due to the modification of the code announced on the Pajooheshyar website by the Ethics Committee of Islamic Azad University of Mashhad Medical Sciences Branch. 2. Minor protocol changes due to the use of Pearl 50000 units of Zahrawi Pharmaceutical Company along with 1000 unit tablets of Omid Porsina Damavand Pharmaceutical Company instead of Pearl 5000 units of Zahrawi Company due to the unavailability of Pearls of 5000 units in the pharmaceutical market. 3. Entering all new and non-new cases of patients with colorectal adenocarcinoma instead of entering new cases alone, due to the number of clients of Reza Radiotherapy and Oncology Sampling Center. 4. Addition of Omid Porsina Damavand pharmaceutical company to sponsors/credit suppliers due to the use of 1000 unit tablets of this company. 5. Removal of Mashhad University Jihad Laboratory from sponsors/credit providers due to the use of sampling center laboratory (Reza Radiotherapy and Oncology Center) in order to save money and time. 6. Measuring the serum level of 25OHD3 at the beginning and end of the intervention instead of measuring it monthly, due to the budget limitation and the unnecessary and lack of significant effect of the monthly measurement of 25OHD3 on the final result of the study.
    1. Modification of the Code of Ethics Committee due to the modification of the code announced on the Pajooheshyar website by the Ethics Committee of Islamic Azad University of Mashhad Medical Sciences Branch. 2. Minor protocol changes due to the use of Pearl 50000 units of Zahrawi Pharmaceutical Company along with 1000 unit tablets of Omid Porsina Damavand Pharmaceutical Company instead of Pearl 5000 units of Zahrawi Company due to the unavailability of Pearls of 5000 units in the pharmaceutical market. 3. Entering all new and non-new cases of patients with colorectal adenocarcinoma instead of entering new cases alone, due to the number of clients of Reza Radiotherapy and Oncology Sampling Center. 4. Addition of Omid Porsina Damavand pharmaceutical company to sponsors/credit suppliers due to the use of 1000 unit tablets of this company. 5. Removal of Mashhad University Jihad Laboratory from sponsors/credit providers due to the use of sampling center laboratory (Reza Radiotherapy and Oncology Center) in order to save money and time. 6. Measuring the serum level of 25OHD3 at the beginning and end of the intervention instead of measuring it monthly, due to the budget limitation and the unnecessary and lack of significant effect of the monthly measurement of 25OHD3 on the final result of the study. 7. Reducing the sample size from 60 people to 45 people due to budget restrictions and increased tariffs and non-cooperation of clients. 8. Addition of 22 Bahman Hospital in Mashhad to the sampling centers to provide the sample size for the study. 9. Removing "Ionized calcium serum level more than 5.6 mg/dL" from the exclusion criteria due to budget limitations and the uncommonness of hypocalcemia and hypercalcemia according to the type of cancer of the study patients. 10. Increasing the age range of participants from 18-65 years to 18-70 years to provide the study sample size.
    ۱. اصلاح کد کمیته اخلاق به علت اصلاح کد اعلام شده در سایت پژوهشیار از سوی کمیته اخلاق دانشگاه آزاد اسلامی واحد علوم پزشکی مشهد. ۲. تغییرات جزئی پروتکل به دلیل استفاده از پرل ۵۰۰۰۰ واحدی شرکت داروسازی زهراوی همراه قرص ۱۰۰۰ واحدی شرکت داروسازی امید پورسینا دماوند به جای پرل ۵۰۰۰ واحدی شرکت زهراوی به علت نا موجود شدن پرل های ۵۰۰۰ واحدی در بازار دارویی. ۳. وارد کردن تمام موارد جدید و غیر جدیدِ مبتلایان آدنوکارسینوم کولورکتال به مطالعه، به جای وارد کردن موارد جدید به تنهایی با توجه به محدودیت تعداد مراجعین مرکز نمونه گیری رادیوتراپی و انکولوژی رضا. ۴. افزودن شرکت داروسازی امید پورسینا دماوند به حامیان/ تامین کنندگان اعتبار به علت استفاده از قرص های ۱۰۰۰ واحدی این شرکت. ۵. حذف آزمایشگاه حهاد دانشگاهی مشهد از حامیان/ تامین کنندگان اعتبار به علت استفاده از آزمایشگاهِ مرکز نمونه گیری ( مرکز رادیوتراپی و انکولوژی رضا) جهت صرفه جویی در هزینه و زمان. ۶. اندازه گیری سطح سرمی 25OHD3 در ابتدا و پایان مداخله به جای اندازه گیری ماهانه‌ی آن، به علت محدودت بودجه و غیر ضروری بودن و عدم تاثیر قابل توجهِ اندازه گیری ماهانه‌ی 25OHD3 بر نتیجه‌ی نهایی مطالعه.
    ۱. اصلاح کد کمیته اخلاق به علت اصلاح کد اعلام شده در سایت پژوهشیار از سوی کمیته اخلاق دانشگاه آزاد اسلامی واحد علوم پزشکی مشهد. ۲. تغییرات جزئی پروتکل به دلیل استفاده از پرل ۵۰۰۰۰ واحدی شرکت داروسازی زهراوی همراه قرص ۱۰۰۰ واحدی شرکت داروسازی امید پورسینا دماوند به جای پرل ۵۰۰۰ واحدی شرکت زهراوی به علت نا موجود شدن پرل های ۵۰۰۰ واحدی در بازار دارویی. ۳. وارد کردن تمام موارد جدید و غیر جدیدِ مبتلایان آدنوکارسینوم کولورکتال به مطالعه، به جای وارد کردن موارد جدید به تنهایی با توجه به محدودیت تعداد مراجعین مرکز نمونه گیری رادیوتراپی و انکولوژی رضا. ۴. افزودن شرکت داروسازی امید پورسینا دماوند به حامیان/ تامین کنندگان اعتبار به علت استفاده از قرص های ۱۰۰۰ واحدی این شرکت. ۵. حذف آزمایشگاه حهاد دانشگاهی مشهد از حامیان/ تامین کنندگان اعتبار به علت استفاده از آزمایشگاهِ مرکز نمونه گیری ( مرکز رادیوتراپی و انکولوژی رضا) جهت صرفه جویی در هزینه و زمان. ۶. اندازه گیری سطح سرمی 25OHD3 در ابتدا و پایان مداخله به جای اندازه گیری ماهانه‌ی آن، به علت محدودت بودجه و غیر ضروری بودن و عدم تاثیر قابل توجهِ اندازه گیری ماهانه‌ی 25OHD3 بر نتیجه‌ی نهایی مطالعه. 7. کاهش حجم نمونه از 60 نفر به 45 نفر به علت محدودیت بودجه با توجه به افزایش تعرفه ها و عدم همکاری مراجعه کنندگان. 8. افزودن بیمارستان 22 بهمن مشهد به مراکز نمونه گیری جهت تامین حجم نمونه مطالعه. 9. حذف " سطح سرمی کلسیم یونیزه بیش از ۵.۶ میلی گرم بر دسی لیتر " از معیار های حذف به علت محدودیت بودجه و ناشایع بودن هایپوکلسمی و هایپرکلسمی با توجه به نوع کنسر بیماران مطالعه. 10. افزایش بازه ی سنی شرکت کنندگان از 18-65 سال به 18-70 سال جهت تامین حجم نمونه مطالعه.
    Complicated diabetes or hypertension
    History of visiting a psychiatrist or psychologist in the last 6 months or taking psychotropic drugs in the last 6 months
    Pregnancy
    Breastfeeding
    Taking vitamin D or vitamin D3 analogs in the last 3 months
    Vitamin D serum level more than 100 ng/ml
    Serum level of ionized calcium more than 5.6 mg/dL
    Complicated diabetes or hypertension
    History of visiting a psychiatrist or psychologist in the last 6 months or taking psychotropic drugs in the last 6 months
    Pregnancy
    Breastfeeding
    Taking vitamin D or vitamin D3 analogs in the last 3 months
    Vitamin D serum level more than 100 ng/ml
    ابتلا به دیابت یا هایپرتانسیون عارضه دار
    سابقه مراجعه به روانپزشک یا روانشناس در ۶ ماه اخیر یا مصرف داروهای سایکوتروپیک در ۶ ماه اخیر
    بارداری
    شیردهی
    مصرف آنالوگ های ویتامین د یا ویتامین د۳ در ۳ ماه اخیر
    سطح سرمی ویتامین د بیش از ۱۰۰ نانوگرم بر میلی لیتر
    سطح سرمی کلسیم یونیزه بیش از ۵.۶ میلی گرم بر دسی لیتر
    ابتلا به دیابت یا هایپرتانسیون عارضه دار
    سابقه مراجعه به روانپزشک یا روانشناس در ۶ ماه اخیر یا مصرف داروهای سایکوتروپیک در ۶ ماه اخیر
    بارداری
    شیردهی
    مصرف آنالوگ های ویتامین د یا ویتامین د۳ در ۳ ماه اخیر
    سطح سرمی ویتامین د بیش از ۱۰۰ نانوگرم بر میلی لیتر
  • Recruitment centers

    #1
    Name of recruitment center - English: 22 Bahman Charitable Hospital
    Name of recruitment center - Persian: بیمارستان خیریه 22 بهمن
    Full name of responsible person - English: Mitra Khazaei
    Full name of responsible person - Persian: میترا خزاعی
    Street address - English: 22 Bahman Charitable Hospital, 39 Shahid Baba Nazar ST, Shahid Baba Nazar HWY,Tollab QTR, Mashhad, Khorasan Razavi Province
    Street address - Persian: استان خراسان رضوی، مشهد، کوی طلاب، مشهد - پیچ دوم تلگرد - شهید بابا نظر 39 صاحبدلان 2 - بیمارستان خیریه 22بهمن
    City - English: Mashhad
    City - Persian: مشهد
    Province: Razavi Khorasan
    Country: Iran (Islamic Republic of)
    Postal code: 19156
    Phone: +98 51 3259 5515
    Fax:
    Email: 22bahmanhospital@gmail.com
    Web page address: http://22bahman.mshdiau.ac.ir/fa/

Protocol summary

Study aim
Investigation the effect of 25-hydroxy vitamin D3 (25OHD3) serum level on anxiety and depression in colorectal adenocarcinoma patients.
Design
A four arm parallel group non-randomised non-blinded before-after designed clinical trial without control group, 60 patients enrolled between march 2023 and march 2024.
Settings and conduct
In this trial, 60 cases of colorectal adenocarcinoma referring to Reza Radiotherapy Center will be included in the study based on the criteria. 50000 unit pearls of cholecalciferol from Zahrawi Pharmaceutical Company and 1000 units tabs from Omid Parsina Pharmaceutical Company will be given based on study's protocol: deficiency group: 50000 units weekly for 8 weeks, then 1000 units daily for 30 days, insufficiency: 1000 units daily. borderline: two days daily 1000 units, then one day off, sufficient: every three days, 1000 units. Serum 25OHD3 level by ELISA method and the anxiety and depression scores of the patients are measured by a questionnaire.
Participants/Inclusion and exclusion criteria
Inclusion criteria: Age 18-65 years old; Ability to write and read in Persian; Ability to answer questionnaire questions.Exclusion criteria: Complicated dibetes or hypertension; History of visiting a psychiatrist or psychologist in the last 6 months or taking psychotropic drugs in the last 6 months؛ Pregnancy; Breastfeeding; Taking vitamin D or vitamin D3 analogs in the last 3 months; Vitamin D serum level more than 100 ng/ml; Serum level of ionized calcium more than 5.6 mg/dL.
Intervention groups
Deficiency group (D): 25OHD3 serum level below 12 ng/ml; Insufficiency group (I): 25OHD3 serum level 12-20 ng/ml; Borderline group (B): 25OHD3 serum level 20-30 ng/ml; Sufficient group (S): 25OHD3 serum level above 30 ng/ml
Main outcome variables
Zung S.D.S score; Zung S.A.S score; 25OHD3 serum level before intervention; 25OHD3 serum level after the end of intervention

General information

Reason for update
1. Modification of the Code of Ethics Committee due to the modification of the code announced on the Pajooheshyar website by the Ethics Committee of Islamic Azad University of Mashhad Medical Sciences Branch. 2. Minor protocol changes due to the use of Pearl 50000 units of Zahrawi Pharmaceutical Company along with 1000 unit tablets of Omid Porsina Damavand Pharmaceutical Company instead of Pearl 5000 units of Zahrawi Company due to the unavailability of Pearls of 5000 units in the pharmaceutical market. 3. Entering all new and non-new cases of patients with colorectal adenocarcinoma instead of entering new cases alone, due to the number of clients of Reza Radiotherapy and Oncology Sampling Center. 4. Addition of Omid Porsina Damavand pharmaceutical company to sponsors/credit suppliers due to the use of 1000 unit tablets of this company. 5. Removal of Mashhad University Jihad Laboratory from sponsors/credit providers due to the use of sampling center laboratory (Reza Radiotherapy and Oncology Center) in order to save money and time. 6. Measuring the serum level of 25OHD3 at the beginning and end of the intervention instead of measuring it monthly, due to the budget limitation and the unnecessary and lack of significant effect of the monthly measurement of 25OHD3 on the final result of the study. 7. Reducing the sample size from 60 people to 45 people due to budget restrictions and increased tariffs and non-cooperation of clients. 8. Addition of 22 Bahman Hospital in Mashhad to the sampling centers to provide the sample size for the study. 9. Removing "Ionized calcium serum level more than 5.6 mg/dL" from the exclusion criteria due to budget limitations and the uncommonness of hypocalcemia and hypercalcemia according to the type of cancer of the study patients. 10. Increasing the age range of participants from 18-65 years to 18-70 years to provide the study sample size.
Acronym
IRCT registration information
IRCT registration number: IRCT20220609055113N1
Registration date: 2022-09-04, 1401/06/13
Registration timing: prospective

Last update: 2023-11-08, 1402/08/17
Update count: 2
Registration date
2022-09-04, 1401/06/13
Registrant information
Name
Reyhaneh Entezari heravi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 51 3765 8488
Email address
r.entezari98@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2023-03-08, 1401/12/17
Expected recruitment end date
2024-03-08, 1402/12/18
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Evaluation of the effect of serum vitamin D levels on anxiety and depression in patients with colorectal adenocarcinoma
Public title
"Effect of vitamin D on anxiety and depresion of patients with colorectal cancer"
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Ability to read and write in Persian Ability to answer questionnaire questions
Exclusion criteria:
Complicated diabetes or hypertension History of visiting a psychiatrist or psychologist in the last 6 months or taking psychotropic drugs in the last 6 months Pregnancy Breastfeeding Taking vitamin D or vitamin D3 analogs in the last 3 months Vitamin D serum level more than 100 ng/ml
Age
From 18 years old to 70 years old
Gender
Both
Phase
2
Groups that have been masked
No information
Sample size
Target sample size: 45
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Islamic Azad University of Mashhad Medical Sciences Branch
Street address
NO. 181 , Resalat 7., Faramarz Abbasi 3., Faramarz Abbasi blvd.
City
Mashhad
Province
Razavi Khorasan
Postal code
9196111111
Approval date
2022-08-15, 1401/05/24
Ethics committee reference number
IR.IAU.MSHD.REC.1401.107

Health conditions studied

1

Description of health condition studied
Anxiety
ICD-10 code
F41.9
ICD-10 code description
Anxiety disorder, unspecified

2

Description of health condition studied
Depression
ICD-10 code
F32.9
ICD-10 code description
Major depressive disorder, single episode, unspecified

Primary outcomes

1

Description
Depression score in Zung questionnaire
Timepoint
Before starting intervention, 90 days after starting to take cholecalciferol
Method of measurement
Zung Self-Rating Depression Scale questionnaire

2

Description
Anxiety score in Zung questionnaire
Timepoint
Before starting intervention, 90 days after starting to take cholecalciferol
Method of measurement
Zung Self-Rating Depression Scale qestionnaire

3

Description
Serum level of 25-hydroxy vitamin D3
Timepoint
Before starting the intervention and 90 days after starting cholecalciferol
Method of measurement
enzyme-linked immunosorbent assay

Secondary outcomes

empty

Intervention groups

1

Description
The first intervention group: patients with a serum level of 25-hydroxyvitamin D3 less than 12 ng/ml receive 8 pearls of 50000 units of cholecalciferol from Zahravi Pharmaceutical Company one pearl weekly for 8 week and then 30 Tabs of 1000 units of cholecalciferol from Omid parsina damavand pharmaceuitical company, daily for 24 days.
Category
Treatment - Drugs

2

Description
The second intervention group: patients with a serum level of 25-hydroxyvitamin D3 of 12-20 ng/ml receive a total of 90 Tabs of 1000 units of cholecalciferol from Omid parsina damavand pharmaceuitical company, one pearl daily for 90 days.
Category
Treatment - Drugs

3

Description
The third intervention group: patients with a serum level of 25-hydroxyvitamin D3 of 20-30 ng/ml will receive a total of 60 pearls of 1000 units of cholecalciferol from Omid parsina damavand pharmaceuitical company accoriding to following command: Two days one pearl daily and then one day off for 3 months.
Category
Treatment - Drugs

4

Description
The fourth intervention group: patients with a serum level of 25-hydroxyvitamin D3 above 30 ng/ml will receive a total of 30 pearls of 1000 units of cholecalciferol from Omid parsina damavand pharmaceuitical company, one pearl every 3 days for 3 months.
Category
Treatment - Drugs

Recruitment centers

1

Recruitment center
Name of recruitment center
Reza Radiotherapy and Oncology Center
Full name of responsible person
Mahdieh Dayani
Street address
Reza Radiotherapy and Oncology Center, 19 Rafsanjani St., Haftom Azar Sq., Rafsanjani Hwy., International Fair Blvd., Mashhad, IRAN
City
Mashhad
Province
Razavi Khorasan
Postal code
9184166759
Phone
+98 51 3500 8000
Fax
+98 51 3522 5671
Email
Info@rroc.ir
Web page address
https://www.rroc.ir/

2

Recruitment center
Name of recruitment center
22 Bahman Charitable Hospital
Full name of responsible person
Mitra Khazaei
Street address
22 Bahman Charitable Hospital, 39 Shahid Baba Nazar ST, Shahid Baba Nazar HWY,Tollab QTR, Mashhad, Khorasan Razavi Province
City
Mashhad
Province
Razavi Khorasan
Postal code
19156
Phone
+98 51 3259 5515
Fax
Email
22bahmanhospital@gmail.com
Web page address
http://22bahman.mshdiau.ac.ir/fa/

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Islamic Azad University
Full name of responsible person
Vahid Pouresmaeil
Street address
Faculty of Medicine, Azad University of Mashhad,14th Imam Khomeini St., 14th Imam Khomeini St., Imam Khomeini Blvd.
City
Mashhad
Province
Razavi Khorasan
Postal code
9133735971
Phone
+98 51 3225 0041
Email
v.pouresmaeil@mshdiau.ac.ir
Web page address
https://mashdms.iau.ir/
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
No
Title of funding source
Islamic Azad university, Mashhad medical science branch, Dr. Mohammad shahinfar medical school
Proportion provided by this source
1
Public or private sector
Private
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

2

Sponsor
Name of organization / entity
Zahravi Pharmaceutical Company
Full name of responsible person
Farhad Kiafar
Street address
No. 23, Darou pakhsh Ave, 18th km Tehran-karaj Makhsous Road,  Alborz- Iran.
City
Tehran
Province
Tehran
Postal code
1397116441
Phone
+98 21 4499 1893
Email
info@zahravipharma.com
Web page address
http://www.zahravi.com/
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
No
Title of funding source
Zahravi Pharmaceutical Company
Proportion provided by this source
1
Public or private sector
Private
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Other

3

Sponsor
Name of organization / entity
Reza Radiotherapy and Oncology Center
Full name of responsible person
Mahdieh Dayani
Street address
Reza Radiotherapy and Oncology Center, 19 Rafsanjani St., Haftom Azar Sq., Rafsanjani Hwy., International Fair Blvd., Mashhad, IRAN
City
Mashhad
Province
Razavi Khorasan
Postal code
9184166759
Phone
+98 51 3500 8000
Email
Info@rroc.ir
Web page address
https://www.rroc.ir/
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
No
Title of funding source
Reza Radiotherapy and Oncology Center
Proportion provided by this source
1
Public or private sector
Private
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Other

4

Sponsor
Name of organization / entity
Omid parsina damavand pharmaceuitical company
Full name of responsible person
Hamid reza Ali asgari
Street address
No. 21, West 12 Alley, Ahmed Qasir St., Argentina Square, Tehran, Tehran
City
Tehran
Province
Tehran
Postal code
1514758511
Phone
+98 21 8604 3645
Fax
+98 21 8604 3485
Email
info@opdpharma.com
Web page address
https://www.opdpharma.com/
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
No
Title of funding source
Omid parsina damavand pharmaceuitical company
Proportion provided by this source
1
Public or private sector
Private
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Other

Person responsible for general inquiries

Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Reyhaneh Entezari heravi
Position
Medical student
Latest degree
A Level or less
Other areas of specialty/work
General Practitioner
Street address
Unit 181, resalat, 7th ALLEY ,No. 3, Faramarz abbasi Ave, Faramarz abbasi Blvd, mashhad city
City
Mashhad
Province
Razavi Khorasan
Postal code
9196111111
Phone
+98 51 3765 8488
Fax
Email
r.entezari98@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Reyhaneh Entezari heravi
Position
Medical student
Latest degree
A Level or less
Other areas of specialty/work
General Practitioner
Street address
Unit 181, resalat, 7th ALLEY ,No. 3, Faramarz abbasi Ave, Faramarz abbasi Blvd, mashhad city
City
Mashhad
Province
Razavi Khorasan
Postal code
9196111111
Phone
+98 51 3765 8488
Fax
Email
r.entezari98@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Reyhaneh Entezari heravi
Position
Medical student
Latest degree
A Level or less
Other areas of specialty/work
General Practitioner
Street address
Unit 181, resalat, 7th ALLEY ,No. 3, Faramarz abbasi Ave, Faramarz abbasi Blvd, mashhad city
City
Mashhad
Province
Razavi Khorasan
Postal code
9196111111
Phone
+98 51 3765 8488
Fax
Email
r.entezari98@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
Only part of the data can be shared, such as information about the main outcome or the like.
When the data will become available and for how long
The access period starts 6 months after the results are published.
To whom data/document is available
It will be available only to researchers working in academic and scientific institutions.
Under which criteria data/document could be used
Based on the criteria of the Ministry of Health, Treatment and Medical Education about clinical trial studies.
From where data/document is obtainable
E-mail: r.entezari.iaum@gmail.com
What processes are involved for a request to access data/document
After obtaining permission from the supervisor, the information will be sent by email.
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